概述

  • 产品名称Anti-SLC25A11抗体
    参阅全部 SLC25A11 一抗
  • 描述
    小鼠单克隆抗体to SLC25A11
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Recombinant Fragment
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-315 of Human SLC25A11

应用

Our Abpromise guarantee covers the use of ab56334 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
IHC-P 1/100. (see Abreview)

靶标

  • 功能Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism.
  • 序列相似性Belongs to the mitochondrial carrier family.
    Contains 3 Solcar repeats.
  • 细胞定位Mitochondrion inner membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • M2OM_HUMAN antibody
    • Mitochondrial 2 oxoglutarate/malate carrier protein antibody
    • Mitochondrial 2-oxoglutarate/malate carrier protein antibody
    • OGC antibody
    • OGCP antibody
    • SLC20A4 antibody
    • SLC25A11 antibody
    • Solute carrier family 20 (oxoglutarate carrier) member 4 antibody
    • Solute carrier family 20 member 4 antibody
    • Solute carrier family 25 (mitochondrial carrier oxoglutarate carrier) member 11 antibody
    • Solute carrier family 25 member 11 antibody
    see all

Anti-SLC25A11 antibody 图像

  • Western blot against tagged recombinant protein immunogen using ab56334 SLC25A11 antibody at 1ug/ml. Predicted band size of immunogen is 61 kDa

Anti-SLC25A11 antibody (ab56334)参考文献

This product has been referenced in:
  • Kelly-Aubert M  et al. GSH monoethyl ester rescues mitochondrial defects in cystic fibrosis models. Hum Mol Genet 20:2745-59 (2011). Read more (PubMed: 21518732) »

See 1 Publication for this product

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Mouse Tissue sections (brain)
Specification brain
Fixative Paraformaldehyde
Antigen retrieval step None
Permeabilization Yes - 0.5% Trition X-100
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: 22°C
Username

Abcam user community

Verified customer

提交于 Feb 12 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"