概述

  • 产品名称Anti-SLC22A8抗体
    参阅全部 SLC22A8 一抗
  • 描述
    小鼠多克隆抗体to SLC22A8
  • 特异性This antibody is reactive against mammalian transfected lysate.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    SLC22A8 (NP_004245, 1 a.a. ~ 542 a.a) human protein.

  • 阳性对照
    • Transfected 293T cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab69883 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 60 kDa).

靶标

  • 功能Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone-3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA).
  • 组织特异性Expressed in kidney.
  • 序列相似性Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
  • 细胞定位Basolateral cell membrane. Localizes on the brush border membrane of the choroid epithelial cells. Localizes to the basolateral membrane of the proximal tubular cells. Localizes on the abluminal and possibly, luminal membrane of the brain capillary endothelial cells (BCEC) (By similarity).
  • Information by UniProt
  • 数据库链接
  • 别名
    • hOAT3 antibody
    • OAT3 antibody
    • Organic anion transporter 3 antibody
    • S22A8_HUMAN antibody
    • SLC22A8 antibody
    • Solute carrier family 22 (organic anion transporter), member 8 antibody
    • Solute carrier family 22 member 8 antibody
    see all

Anti-SLC22A8 antibody 图像

  • All lanes : Anti-SLC22A8 antibody (ab69883) at 1/500 dilution

    Lane 1 : SLC22A8 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 60 kDa
    Observed band size : 50 kDa (why is the actual band size different from the predicted?)

Anti-SLC22A8 antibody (ab69883)参考文献

This product has been referenced in:
  • Kunin M  et al. Urinary organic anion transporter protein profiles in AKI. Nephrol Dial Transplant 27:1387-95 (2012). WB ; Human . Read more (PubMed: 21945944) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab69883.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"