概述

  • 产品名称
    Anti-SLC19A3抗体
  • 描述
    兔多克隆抗体to SLC19A3
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 225-255 of Human SLC19A3, conjugated to KLH.

  • 阳性对照
    • NIH-H292 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab103950 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 56 kDa.

靶标

  • 相关性
    SLC19A3 is a member of the reduced folate family of micronutrient transporter genes. It is a ubiquitously expressed transmembrane thiamine transporter that lacks folate transport activity yet mediates high affinity thiamine uptake propably via a proton anti-port mechanism. Mutations in this gene cause biotin-responsive basal ganglia disease (BBGD); a recessive disorder manifested in childhood that progresses to chronic encephalopathy, dystonia, quadriparesis, and death if untreated. Patients with BBGD have bilateral necrosis in the head of the caudate nucleus and in the putamen. Mutations in this gene also cause a Wernicke's-like encephalopathy.
  • 细胞定位
    Plasma membrane
  • 数据库链接
  • 别名
    • Solute carrier family 19 member 3 antibody
    • Thiamine transporter 2 antibody
    • thTr 2 antibody
    • THTR2 antibody

图片

  • Anti-SLC19A3 antibody (ab103950) at 1/100 dilution + NIH-H292 cell lysate at 35 µg

    Predicted band size : 56 kDa

实验方案

文献

This product has been referenced in:
  • Ghosal A  et al. Enterotoxigenic Escherichia coli infection and intestinal thiamin uptake: studies with intestinal epithelial Caco-2 monolayers. Am J Physiol Cell Physiol 305:C1185-91 (2013). Read more (PubMed: 24133060) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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