概述

  • 产品名称Anti-SLC16A3抗体
    参阅全部 SLC16A3 一抗
  • 描述
    兔多克隆抗体to SLC16A3
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthesized peptide derived from internal region of human SLC16A3.

  • 阳性对照
    • Extracts from LOVO cells

性能

应用

Our Abpromise guarantee covers the use of ab74109 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 49 kDa.
ELISA 1/40000.

靶标

  • 功能Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.
  • 组织特异性Highly expressed in skeletal muscle.
  • 序列相似性Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 形式Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family 16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 and MCT2, are characterized by 12 predicted transmembrane domains.
  • 别名
    • MCT 4 antibody
    • MCT3 antibody
    • MCT4 antibody
    • Monocarboxylate transporter 3 antibody
    • Monocarboxylate transporter 4 antibody
    • MOT4_HUMAN antibody
    • SLC16A3 antibody
    • Solute carrier family 16 member 3 antibody
    see all

Anti-SLC16A3 antibody 图像

  • All lanes : Anti-SLC16A3 antibody (ab74109) at 1/500 dilution

    Lane 1 : extracts from LOVO cells
    Lane 2 : extracts from LOVO cells with immunizing peptide at 5 µg

    Lysates/proteins at 10 µg per lane.


    Predicted band size : 49 kDa
    Observed band size : 49 kDa

Anti-SLC16A3 antibody (ab74109)参考文献

This product has been referenced in:
  • Ghorbel MT  et al. Changes in renal medulla gene expression in a pre-clinical model of post cardiopulmonary bypass acute kidney injury. BMC Genomics 15:916 (2014). Read more (PubMed: 25331815) »

See 1 Publication for this product

Product Wall

Application Western blot
Loading amount 30 µg
Gel Running Conditions Reduced Denaturing (10% 37.5:1)
Sample Pig Tissue lysate - whole (Skeletal Muscle)
Specification Skeletal Muscle
Blocking step Thermo Starting Block 37542 as blocking agent for 30 minute(s) · Concentration: 100% · Temperature: 22°C
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Verified customer

提交于 Dec 10 2013

Thank you for providing that information. It allows me to more fully understand the results that you have been observing.

There are a few further things I would like to clarify:

You mentioned that the anti-MCT1 has also been proving...

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I ha...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"