概述

  • 产品名称Anti-SLC12A6抗体
    参阅全部 SLC12A6 一抗
  • 描述
    山羊多克隆抗体to SLC12A6
  • 特异性ab77338 is expected to recognise all 6 reported isofoms (NP_598408.1; NP_005126.1; NP_001035959.1; NP_001035960.1; NP_001035961.1; NP_001035962.1).
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Orangutan
  • 免疫原

    Synthetic peptide:

    SRHIDVCSKTKE

    , corresponding to internal sequence amino acids 384-395 of Human SLC12A6 (NP_001035959.1; NP_001035960.1; NP_001035961.1; NP_001035962.1; NP_005126.1; NP_598408.1.)

  • 阳性对照
    • Human Heart and kidney lysates.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab77338 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab77338 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明Peptide ELISA: Use at an assay dependent dilution. Antibody detection limit dilution 1/16,000.
    WB: Use at a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 128 kDa (predicted molecular weight: 128 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Mediates electroneutral potassium-chloride cotransport. May be activated by cell swelling. May contribute to cell volume homeostasis in single cells.
    • 组织特异性Highly expressed in heart, brain and kidney. Detected at lower levels in skeletal muscle, placenta, lung and pancreas. Detected in umbilical vein endothelial cells. Isoform 2 is more abundant in kidney. Isoform 5 is testis specific. Expressed in the proximal tubule of the kidney (at protein level).
    • 疾病相关Agenesis of the corpus callosum, with peripheral neuropathy
    • 序列相似性Belongs to the SLC12A transporter family.
    • 翻译后修饰N-glycosylated.
    • 细胞定位Basolateral cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • ACCPN antibody
      • Electroneutral potassium-chloride cotransporter 3 antibody
      • Furosemide sensitive KCl cotransporter 3 antibody
      • Gaxp antibody
      • K-Cl cotransporter 3 antibody
      • KCC 3 antibody
      • KCC 3A antibody
      • KCC 3B antibody
      • KCC3 A antibody
      • KCC3 antibody
      • KCC3 B antibody
      • KCC3A antibody
      • KCC3B antibody
      • Potassium chloride cotransporter 3 antibody
      • Potassium chloride cotransporter KCC3a S3 antibody
      • S12A6_HUMAN antibody
      • SLC12 A6 antibody
      • SLC12A 6 antibody
      • SLC12A6 antibody
      • Solute carrier family 12 (potassium/chloride transporters), member 6 antibody
      • Solute carrier family 12 member 6 antibody
      • Solute carrier family 12, member 6 antibody
      see all

    Anti-SLC12A6 antibody 图像

    • Anti-SLC12A6 antibody (ab77338) at 0.1 µg/ml + Human Heart lysate (in RIPA buffer) at 35 µg

      Predicted band size : 128 kDa
      Observed band size : 128 kDa

    Anti-SLC12A6 antibody (ab77338)参考文献

    ab77338 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"