概述
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产品名称Anti-SLC10A2抗体
参阅全部 SLC10A2 一抗 -
描述山羊多克隆抗体to SLC10A2
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宿主Goat
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经测试应用适用于: WB, ELISAmore details
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种属反应性与反应: Mouse
预测可用于: Rat
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免疫原
Synthetic peptide:
C-DETNKGFQPDEK
, corresponding to C terminal amino acids 337-348 of Mouse SLC10A2 (NP_035518.1). -
阳性对照
- Mouse Small Intestine lysate.
性能
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形式Liquid
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存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
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存储溶液Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris saline, pH 7.3 -
Concentration information loading... -
纯度Immunogen affinity purified
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克隆多克隆
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同种型IgG
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研究领域
相关产品
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Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab82170 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | ||
| ELISA |
应用说明
Peptide ELISA: Antibody detection limit dilution 1/32000.
WB: Use at a concentration of 0.5 - 1.5 µg/ml. Predicted molecular weight: 38 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
WB: Use at a concentration of 0.5 - 1.5 µg/ml. Predicted molecular weight: 38 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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功能Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism.
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疾病相关Defects in SLC10A2 are a cause of primary bile acid malabsorption (PBAM) [MIM:613291]. PBAM is an idiopathic intestinal disorder associated with congenital diarrhea, steatorrhea, interruption of the enterohepatic circulation of bile acids, and reduced plasma cholesterol levels.
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序列相似性Belongs to the sodium:bile acid symporter family.
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细胞定位Membrane.
- Information by UniProt
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数据库链接
- Entrez Gene: 20494 Mouse
- Entrez Gene: 29500 Rat
- SwissProt: P70172 Mouse
- SwissProt: Q62633 Rat
- Unigene: 3500 Mouse
- Unigene: 85891 Rat
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别名
- Apical sodium dependent bile acid transporter antibody
- Apical sodium- dependent bile acid transporter antibody
- Apical sodium-dependent bile acid transporter antibody
see all
图片
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Western blot - SLC10A2 antibody (ab82170)Anti-SLC10A2 antibody (ab82170) at 0.5 µg/ml + Mouse small intestine lysate in RIPA buffer at 35 µg
Developed using the ECL technique.
Predicted band size: 38 kDa
Observed band size: 35 kDa (why is the actual band size different from the predicted?)
Primary incubation was 1 hour.
文献
ab82170 has not yet been referenced specifically in any publications.
客户评价及客户问答
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"