Anti-SLC10A1/NTCP1抗体(ab131084)
Key features and details
- Rabbit polyclonal to SLC10A1/NTCP1
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
概述
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产品名称
Anti-SLC10A1/NTCP1抗体
参阅全部 SLC10A1/NTCP1 一抗 -
描述
兔多克隆抗体to SLC10A1/NTCP1 -
宿主
Rabbit -
经测试应用
适用于: IHC-P, WBmore details -
种属反应性
与反应: Mouse, Rat, Human -
免疫原
Synthetic peptide corresponding to Human SLC10A1/NTCP1 aa 141-154 (internal sequence).
Sequence:YSRGIYDGDLKDKV
Database link: Q14973 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
Preservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
Constituents: 2.5% BSA, 0.1% Dibasic monohydrogen sodium phosphate, 0.45% Sodium chloride -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab131084于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P | (2) |
Use at an assay dependent concentration.
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WB | (3) |
Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 38 kDa.
|
说明 |
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IHC-P
Use at an assay dependent concentration. |
WB
Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 38 kDa. |
靶标
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功能
The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium. -
序列相似性
Belongs to the sodium:bile acid symporter family. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 6554 Human
- Entrez Gene: 20493 Mouse
- Entrez Gene: 24777 Rat
- Omim: 182396 Human
- SwissProt: Q14973 Human
- SwissProt: O08705 Mouse
- SwissProt: P26435 Rat
- Unigene: 952 Human
see all -
别名
- Cell growth-inhibiting gene 29 protein antibody
- GIG29 antibody
- Growth inhibiting protein 29 antibody
see all
图片
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All lanes : Anti-SLC10A1/NTCP1 antibody (ab131084) at 0.5 µg
Lane 1 : Rat liver lysate
Lane 2 : Mouse liver lysate
Lysates/proteins at 50 µg per lane.
Predicted band size: 38 kDa -
Paraffin-embedded human liver cancer tissue stained for SLC10A1/NTCP1 using ab131084 at 1 µg/ml in immunohistochemical analysis.
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IHC image of SLC10A1/NTCP1 staining in human liver formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab131084, 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.
数据表及文件
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SDS download
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Datasheet download
文献 (18)
ab131084 被引用在 18 文献中.
- Yang Y et al. Human menstrual blood-derived stem cell transplantation suppresses liver injury in DDC-induced chronic cholestasis. Stem Cell Res Ther 13:57 (2022). PubMed: 35123555
- Li JY et al. New and effective method to develop primary hepatocytes from liver cancer patients. Exp Biol Med (Maywood) 247:972-981 (2022). PubMed: 35470702
- Komatsu H et al. Signature of chronic hepatitis B virus infection in nails and hair. BMC Infect Dis 22:431 (2022). PubMed: 35509029
- Wang W et al. Transcriptome and Gut Microbiota Profiling Analysis of ANIT-Induced Cholestasis and the Effects of Da-Huang-Xiao-Shi Decoction Intervention. Microbiol Spectr 10:e0324222 (2022). PubMed: 36409145
- Zheng Z et al. A High Hepatic Uptake of Conjugated Bile Acids Promotes Colorectal Cancer-Associated Liver Metastasis. Cells 11:N/A (2022). PubMed: 36497071