概述

  • 产品名称Anti-SLAMF6抗体
    参阅全部 SLAMF6 一抗
  • 描述
    小鼠多克隆抗体to SLAMF6
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Fusion protein:

    FVLKRIXXLSKKXDKYFXSSKYIAWPLQGWQATFGGGDHLENLYFQRRHG RSYRYRCSLQPHSITGCTCGGQPTGRGPAAMAEPPCRSAGKRCGTARQPA GGAERRPVSDLLSGSVQGPGLPVYSRAADSHHLSHRSVLPNQSEPAVGHK PMSANPRGCGGVECIDHSGLGSSSTSMLSMLCTCIGIHRDLTICLARFGD

    , corresponding to amino acids 27/240 of Mouse LY108

  • 常规说明Produced from outbred CD1 mice


    This antibody was raised by a genetic immunization technique. Genetic immunization can be used to generate antibodies by directly delivering antigen-coding DNA into the animal, rather than injecting a protein or peptide (Tang et al. PubMed: 1545867; Chambers and Johnston PubMed: 12910245; Barry and Johnston PubMed: 9234514). The animal`s cells produce the protein, which stimulates the animal`s immune system to produce antibodies against that particular protein. A vector coding for a partial fusion protein was used for genetic immunisation of a mouse and the resulting serum was tested in Western blot against an E.coli lysate containing that partial fusion protein. Genetic immunization offers enormous advantages over the traditional protein-based immunization method. DNA is faster, cheaper and easier to produce and can be produced by standard techniques readily amenable to automation. Furthermore, the antibodies generated by genetic immunization are usually of superior quality with regard to specificity, affinity and recognizing the native protein.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液Constituents: 50% Glycerol
  • 纯度Whole antiserum
  • Primary antibody说明This antibody was raised by a genetic immunization technique. Genetic immunization can be used to generate antibodies by directly delivering antigen-coding DNA into the animal, rather than injecting a protein or peptide (Tang et al. PubMed: 1545867; Chambers and Johnston PubMed: 12910245; Barry and Johnston PubMed: 9234514). The animal`s cells produce the protein, which stimulates the animal`s immune system to produce antibodies against that particular protein. A vector coding for a partial fusion protein was used for genetic immunisation of a mouse and the resulting serum was tested in Western blot against an E.coli lysate containing that partial fusion protein. Genetic immunization offers enormous advantages over the traditional protein-based immunization method. DNA is faster, cheaper and easier to produce and can be produced by standard techniques readily amenable to automation. Furthermore, the antibodies generated by genetic immunization are usually of superior quality with regard to specificity, affinity and recognizing the native protein.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab21615 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Predicted molecular weight: 37 kDa.

This antibody has been tested in Western blot against an E.coli lysate containing the partial recombinant fusion protein used as an immunogen. We have no data on detection of endogenous protein.

靶标

  • 功能Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors.
  • 组织特异性Expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes.
  • 序列相似性Contains 1 Ig-like (immunoglobulin-like) domain.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Activating NK receptor antibody
    • CD352 antibody
    • KALI antibody
    • KALIb antibody
    • LY108 antibody
    • MGC104953 antibody
    • Natural killer T and B cell antigen antibody
    • NK T B antigen antibody
    • NK-, T-, and B-cell antigen antibody
    • NK-T-B-antigen antibody
    • NTB A antibody
    • NTB-A antibody
    • NTBA antibody
    • NTBA receptor antibody
    • SF2000 antibody
    • SLAF6_HUMAN antibody
    • SLAM family member 6 antibody
    • SLAM family member 6 precursor antibody
    • SLAM Family Receptor antibody
    • Slamf6 antibody
    see all

Anti-SLAMF6 antibody 图像

  • All lanes : Anti-SLAMF6 antibody (ab21615) at 1/1000 dilution

    Lane 1 : Total protein extract from E. coli with ~50ng to 100ng of a negative control fusion protein with an irrelevant antigen at 20 ug
    Lane 2 : Total protein extract from E. coli with ~50ng to 500ng of the antigen fusion protein at 20 ug

    Secondary
    Rabbit anti-mouse IgG + IgM, (H+L) horseradish peroxidase conjugated at 1/5000 dilution

    Predicted band size : 37 kDa

Anti-SLAMF6 antibody (ab21615)参考文献

ab21615 has not yet been referenced specifically in any publications.

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