概述

  • 产品名称
  • 描述
    兔多克隆抗体to SLAIN2
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Guinea pig, Cow
  • 免疫原

    Synthetic peptide designed within residues: SAKSGGGPGS GPRRTSSEEL RDATSLLAAG EGGLLDEVEP LRPDELERLS, corresponding to amino acids 71 - 119 of Human SLAIN2 (NP_065897).

  • 阳性对照
    • Fetal thymus lysate

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG

应用

Our Abpromise guarantee covers the use of ab94863 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 63 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Required for normal structure of the microtubule cytoskeleton during interphase.
  • 组织特异性
    Widely expressed with highest levels in adult liver, testis and ovary, and lowest levels in adult pancreas and spleen and in fetal brain.
  • 序列相似性
    Belongs to the SLAIN motif-containing family.
  • 结构域
    The N-terminus forms a two-stranded coiled coil.
  • 翻译后修饰
    Is highly phosphorylated during mitosis, but not during interphase. The highly phosphorylated form does not localize at microtubule plus ends and does not interact with MAPRE1 or CKAP5.
  • 细胞定位
    Cytoplasm > cytoskeleton. Colocalizes with microtubules. Detected at the plus end of growing microtubules.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ21611 antibody
    • KIAA1458 antibody
    • SLAI2_HUMAN antibody
    • SLAIN motif containing 2 antibody
    • SLAIN motif family member 2 antibody
    • SLAIN motif-containing protein 2 antibody
    • SLAIN2 antibody
    see all

图片

  • Anti-SLAIN2 antibody (ab94863) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal thymus lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 63 kDa

实验方案

文献

ab94863 has not yet been referenced specifically in any publications.

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