Anti-Skp1抗体, prediluted (ab41866)

概述

  • 产品名称Anti-Skp1抗体, prediluted
    参阅全部 Skp1 一抗
  • 描述
    兔多克隆抗体to Skp1, prediluted
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide corresponding to C-terminal of human Skp1.

  • 阳性对照
    • Breast carcinoma.

性能

应用

Our Abpromise guarantee covers the use of ab41866 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Use neat.
WB Use at an assay dependent concentration.

靶标

  • 功能Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(Cyclin F) directs ubiquitination of CP110.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Belongs to the SKP1 family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cyclin A/CDK2 associated p19 antibody
    • Cyclin A/CDK2 associated protein p19 antibody
    • Cyclin-A/CDK2-associated protein p19 antibody
    • EMC19 antibody
    • MGC34403 antibody
    • OCP 2 antibody
    • OCP II antibody
    • OCP II protein antibody
    • OCP-2 antibody
    • OCP-II antibody
    • OCP2 antibody
    • OCPII antibody
    • Organ of Corti protein 2 antibody
    • Organ of Corti protein II antibody
    • OTTHUMP00000159379 antibody
    • OTTHUMP00000159380 antibody
    • OTTHUMP00000228275 antibody
    • OTTHUMP00000228276 antibody
    • OTTHUMP00000228278 antibody
    • OTTHUMP00000228279 antibody
    • OTTHUMP00000228281 antibody
    • p19A antibody
    • p19skp1 antibody
    • RNA polymerase II elongation factor like protein antibody
    • RNA polymerase II elongation factor like protein OCP2 antibody
    • RNA polymerase II elongation factor-like protein antibody
    • S phase kinase associated protein 1 antibody
    • S phase kinase associated protein 1A antibody
    • S phase kinase associated protein 1A p19A antibody
    • S-phase kinase-associated protein 1 antibody
    • SIII antibody
    • Skp 1 antibody
    • SKP 1A antibody
    • skp1 antibody
    • SKP1_HUMAN antibody
    • SKP1A antibody
    • TCEB1L antibody
    • Transcription Elongation Factor B 1 like antibody
    • Transcription elongation factor B antibody
    • Transcription elongation factor B SIII polypeptide 1 like antibody
    see all

Anti-Skp1 antibody, prediluted 图像

  • Ab41866 staining human Skp1 in human breast carcinoma by immunohistochemistry using formalin fixed paraffin embedded tissue.
  • Anti-Skp1 antibody, prediluted (ab41866) at 1/25 dilution + lysate prepared from NIH3T3 cells

Anti-Skp1 antibody, prediluted (ab41866)参考文献

ab41866 has not yet been referenced specifically in any publications.

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