Anti-SKIP抗体(ab67715)
Key features and details
- Mouse polyclonal to SKIP
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-SKIP抗体 -
描述
小鼠多克隆抗体to SKIP -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Recombinant full length protein within Human SKIP aa 1-450. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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阳性对照
- Transfected 293T cell lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.4
Constituent: PBS -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab67715于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB | (1) |
1/500 - 1/1000. Predicted molecular weight: 51 kDa.
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说明 |
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WB
1/500 - 1/1000. Predicted molecular weight: 51 kDa. |
靶标
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功能
Inositol 5-phosphatase which acts on inositol 1,4,5-trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-triphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate. May negatively regulate assembly of the actin cytoskeleton. -
组织特异性
Ubiquitously expressed with highest levels in skeletal muscle, heart and kidney. -
序列相似性
Belongs to the inositol-1,4,5-trisphosphate 5-phosphatase type II family. -
细胞定位
Endoplasmic reticulum. Following stimulation with EGF, translocates to membrane ruffles. - Information by UniProt
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数据库链接
- Entrez Gene: 51763 Human
- Omim: 607875 Human
- SwissProt: Q9BT40 Human
- Unigene: 632238 Human
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别名
- 43 kDa form skeletal muscle and kidney enriched inositol phosphatase antibody
- Inositol polyphosphate 5-phosphatase K antibody
- INP5K_HUMAN antibody
see all
图片
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All lanes : Anti-SKIP antibody (ab67715) at 1/500 dilution
Lane 1 : SKIP transfected 293T cell lysate
Lane 2 : non transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size: 51 kDa
Observed band size: 51 kDa
数据表及文件
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Datasheet download
文献 (1)
ab67715 被引用在 1 文献中.
- Wu MY et al. SNW1 is a critical regulator of spatial BMP activity, neural plate border formation, and neural crest specification in vertebrate embryos. PLoS Biol 9:e1000593 (2011). WB . PubMed: 21358802