Anti-SKA2抗体(ab91551)

概述

  • 产品名称Anti-SKA2抗体
    参阅全部 SKA2 一抗
  • 描述
    兔多克隆抗体to SKA2
  • 特异性This antibody is specific for SKA2 and will not crossreact with SKA1 or SKA3.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    A 15 amino acid peptide from near the N terminus of Human SKA2 (NP_872426).

  • 阳性对照
    • 3T3 cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Affinity chromatography purified via peptide column
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab91551 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明ELISA: Use at an assay dependent dilution.
    WB: Use at a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 14 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it is required for SKA1 localization.
    • 序列相似性Belongs to the SKA2 family.
    • 细胞定位Cytoplasm > cytoskeleton > spindle. Chromosome > centromere > kinetochore. Localizes to the outer kinetochore and spindle microtubules during mitosis in a NDC80 complex-dependent manner. Localizes to both the mitotic spindle and kinetochore-associated proteins.
    • Information by UniProt
    • 数据库链接
    • 别名
      • FAM33A antibody
      • Family with sequence similarity 33, member A antibody
      • FLJ12758 antibody
      • MGC110975 antibody
      • Protein FAM33A antibody
      • SKA 2 antibody
      • SKA2 antibody
      • SKA2_HUMAN antibody
      • Spindle and kinetochore associated complex subunit 2 antibody
      • Spindle and kinetochore associated protein 2 antibody
      • Spindle and kinetochore-associated protein 2 antibody
      • Spindle and KT (kinetochore) associated 2 antibody
      • Spindle and KT associated 2 antibody
      see all

    Anti-SKA2 antibody 图像

    • Lane 1 : Anti-SKA2 antibody (ab91551) at 0.5 µg/ml
      Lane 2 : Anti-SKA2 antibody (ab91551) at 1 µg/ml

      Lane 1 : 3T3 cell lysate
      Lane 2 : 3T3 cell lysate

      Lysates/proteins at 15 µg per lane.


      Predicted band size : 14 kDa

    Anti-SKA2 antibody (ab91551)参考文献

    ab91551 has not yet been referenced specifically in any publications.

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