Anti-SIT抗体[SIT-01] (Phycoerythrin) (ab36418)

概述

  • 产品名称
    Anti-SIT抗体[SIT-01] (Phycoerythrin)
    参阅全部 SIT 一抗
  • 描述
    小鼠单克隆抗体[SIT-01] to SIT (Phycoerythrin)
  • 偶联物
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • 特异性
    ab36418 reacts with SIT.
  • 经测试应用
    适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment (Human) Bacterially produced recombinant intracellular fragment of human SIT.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C.
  • 存储溶液
    Preservative: 15mM Sodium Azide
    Constituents: 0.2% BSA, PBS
  • Concentration information loading...
  • 纯化说明
    The conjugate was purified by size-exclusion chromatography
  • 克隆
    单克隆
  • 克隆编号
    SIT-01
  • 同种型
    IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab36418 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt 1/50.

靶标

  • 功能
    Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. Involved in positive selection of T-cells.
  • 组织特异性
    Specifically expressed in T- and B-cells. Present in plasma cells but not in germinal center B-cells (at protein level). Expressed in T- and B-cell lymphoma.
  • 翻译后修饰
    Phosphorylated on tyrosines by LCK, FYN or ZAP70 upon TCR activation; which leads to the recruitment of PTPN11, GRB2 and CSK.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • gp30/40 antibody
    • SHP intracting transmembrane adapter protein antibody
    • SHP2-interacting transmembrane adapter protein antibody
    • Signaling threshold-regulating transmembrane adapter 1 antibody
    • SIT antibody
    • Sit1 antibody
    • SIT1_HUMAN antibody
    • Suppression inducing transmembrane adapter 1 antibody
    • Suppression-inducing transmembrane adapter 1 antibody
    see all

图片

  • Flow Cytometry analysis of human peripheral blood cells labeling SIT with Anti-SIT antibody [SIT-01] (Phycoerythrin) (ab36418).

文献

ab36418 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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