概述

  • 产品名称Anti-SIPA1抗体
    参阅全部 SIPA1 一抗
  • 描述
    兔多克隆抗体to SIPA1
  • 特异性At least three isoforms of SIPA1 are known to exist; this antibody will recognize all three isoforms. This antibody is specific for SIPA1 and will not recognize the other SIPA1 family of proteins.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    uman brain tissue lysate 19 amino acids from near the N-terminus of Human SIPA1 (AAH10492).

  • 阳性对照
    • Human brain tissue lysate

性能

应用

Our Abpromise guarantee covers the use of ab124202 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 112 kDa.

靶标

  • 功能GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting it to the putatively inactive GDP-bound state.
  • 组织特异性Expressed in fetal as well as in adult tissues. Expressed abundantly in the lymphoid tissues such as thymus, spleen and peripheral blood lymphocytes and also shows a significant expression in the spinal cord.
  • 序列相似性Contains 1 PDZ (DHR) domain.
    Contains 1 Rap-GAP domain.
  • 细胞定位Nucleus. Cytoplasm > perinuclear region. Endomembrane system. Mostly localized in the perinuclear membraneous region.
  • Information by UniProt
  • 数据库链接
  • 别名
    • GTPase activating protein Spa 1 antibody
    • GTPase-activating protein Spa-1 antibody
    • MGC102688 antibody
    • MGC17037 antibody
    • p130 SPA-1 antibody
    • p130 SPA1 antibody
    • Signal induced proliferation associated 1 antibody
    • Signal induced proliferation associated gene 1 antibody
    • Signal induced proliferation associated protein 1 antibody
    • Signal-induced proliferation-associated protein 1 antibody
    • SIPA 1 antibody
    • Sipa-1 antibody
    • Sipa1 antibody
    • SIPA1_HUMAN antibody
    • Spa1 antibody
    see all

Anti-SIPA1 antibody 图像

  • Anti-SIPA1 antibody (ab124202) at 1 µg/ml + Human brain tissue lysate at 15 µg

    Predicted band size : 112 kDa

Anti-SIPA1 antibody (ab124202)参考文献

ab124202 has not yet been referenced specifically in any publications.

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