概述

  • 产品名称
  • 描述
    兔多克隆抗体to Sin3b
  • 经测试应用
    适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 165-325 of Human Sin3b.

  • 阳性对照
    • HCT116 whole cell lysate and MCF7 xenograft tissue

性能

应用

Our Abpromise guarantee covers the use of ab101841 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 133 kDa.
IHC-P 1/100 - 1/500.

靶标

  • 相关性
    Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
  • 细胞定位
    Nuclear
  • 数据库链接
  • 别名
    • Histone deacetylase complex subunit Sin3b antibody
    • Paired amphipathic helix protein Sin3b antibody
    • SIN3 homolog B transcription regulator antibody
    • SIN3 transcription regulator family member B antibody
    • SIN3 transcription regulator homolog B antibody
    • Transcriptional corepressor Sin3b antibody
    see all

图片

  • Anti-Sin3b antibody (ab101841) at 1/500 dilution + HCT116 whole cell lysate at 30 µg

    Predicted band size : 133 kDa
  • Immunohistochemical analysis of Sin3b in paraffin embedded MCF7 xenograft, using ab101841 at a 1/100 dilution.

文献

ab101841 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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