Recombinant fragment, corresponding to a region within amino acids 165-325 of Human Sin3b.
HCT116 whole cell lysate and MCF7 xenograft tissue
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 20% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
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Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 133 kDa.
1/100 - 1/500.
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
Histone deacetylase complex subunit Sin3b antibody
Paired amphipathic helix protein Sin3b antibody
SIN3 homolog B transcription regulator antibody
Western blot - Sin3b antibody (ab101841)
Anti-Sin3b antibody (ab101841) at 1/500 dilution + HCT116 whole cell lysate at 30 µg
Predicted band size : 133 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Sin3b antibody (ab101841)
Immunohistochemical analysis of Sin3b in paraffin embedded MCF7 xenograft, using ab101841 at a 1/100 dilution.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"