RabMAb

Anti-Silencer of Death Domain抗体[EPR3596] (ab108988)

概述

  • 产品名称Anti-Silencer of Death Domain抗体[EPR3596]
    参阅全部 Silencer of Death Domain 一抗
  • 描述
    兔单克隆抗体[EPR3596] to Silencer of Death Domain
  • 经测试应用适用于: WB, Flow Cyt, ICC/IFmore details
    不适用于: IHC-P or IP
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to residues in Human Silencer of Death Domain (UniProt O95429).

  • 阳性对照
    • WB: HeLa, HepG2, and Molt-4 cell lysates ICC/IF: HeLa cells
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab108988 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 65 kDa (predicted molecular weight: 50 kDa).
Flow Cyt 1/10 - 1/100. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
ICC/IF 1/100 - 1/250.
  • 应用说明Is unsuitable for IHC-P or IP.
  • 靶标

    • 功能Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling.
    • 组织特异性Ubiquitous.
    • 序列相似性Contains 1 BAG domain.
    • 细胞定位Cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • BAG 4 antibody
      • BAG family molecular chaperone regulator 4 antibody
      • BAG-4 antibody
      • BAG4 antibody
      • BAG4_HUMAN antibody
      • Bcl 2 associated athanogene 4 antibody
      • Bcl-2-associated athanogene 4 antibody
      • BCL2 associated athanogene 4 antibody
      • Silencer of death domains antibody
      • SODD antibody
      see all

    Anti-Silencer of Death Domain antibody [EPR3596] 图像

    • All lanes : Anti-Silencer of Death Domain antibody [EPR3596] (ab108988) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : HepG2 cell lysate
      Lane 3 : Molt-4 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit IgG at 1/2000 dilution

      Predicted band size : 50 kDa
      Observed band size : 65 kDa (why is the actual band size different from the predicted?)
    • Immunofluorescent staining of Silencer of Death Domain in HeLa cells, using ab108988 at a 1/100 dilution.

    Anti-Silencer of Death Domain antibody [EPR3596] (ab108988)参考文献

    ab108988 has not yet been referenced specifically in any publications.

    Product Wall

    The Anti-Silencer of Death Domain antibody ab108988 is unlikely to react with the sequence you provided. The immunogen for the antibody is a 15 amino acid peptide and alignment with your sequence returns only 4 matching amino acids, PPQ-P.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"