重组
RabMAb

Anti-Silencer of Death Domain抗体[EPR3596] (ab108988)

概述

  • 产品名称
    Anti-Silencer of Death Domain抗体[EPR3596]
    参阅全部 Silencer of Death Domain 一抗
  • 描述
    兔单克隆抗体[EPR3596] to Silencer of Death Domain
  • 经测试应用
    适用于: WB, Flow Cyt, ICC/IFmore details
    不适用于: IHC-P or IP
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to residues in Human Silencer of Death Domain (UniProt O95429).

  • 阳性对照
    • WB: HeLa, HepG2, and Molt-4 cell lysates ICC/IF: HeLa cells
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab108988 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 65 kDa (predicted molecular weight: 50 kDa).
Flow Cyt 1/10 - 1/100. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
ICC/IF 1/100 - 1/250.
  • 应用说明
    Is unsuitable for IHC-P or IP.
  • 靶标

    • 功能
      Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling.
    • 组织特异性
      Ubiquitous.
    • 序列相似性
      Contains 1 BAG domain.
    • 细胞定位
      Cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • BAG 4 antibody
      • BAG family molecular chaperone regulator 4 antibody
      • BAG-4 antibody
      • BAG4 antibody
      • BAG4_HUMAN antibody
      • Bcl 2 associated athanogene 4 antibody
      • Bcl-2-associated athanogene 4 antibody
      • BCL2 associated athanogene 4 antibody
      • Silencer of death domains antibody
      • SODD antibody
      see all

    Anti-Silencer of Death Domain antibody [EPR3596] 图像

    • All lanes : Anti-Silencer of Death Domain antibody [EPR3596] (ab108988) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : HepG2 cell lysate
      Lane 3 : Molt-4 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit IgG at 1/2000 dilution

      Predicted band size : 50 kDa
      Observed band size : 65 kDa (why is the actual band size different from the predicted?)
    • Immunofluorescent staining of Silencer of Death Domain in HeLa cells, using ab108988 at a 1/100 dilution.

    Anti-Silencer of Death Domain antibody [EPR3596] (ab108988)参考文献

    ab108988 has not yet been referenced specifically in any publications.

    Product Wall

    The Anti-Silencer of Death Domain antibody ab108988 is unlikely to react with the sequence you provided. The immunogen for the antibody is a 15 amino acid peptide and alignment with your sequence returns only 4 matching amino acids, PPQ-P.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    注册