Anti-Signal肽peptidase-like 2B抗体(ab43856)

概述

  • 产品名称Anti-Signal肽peptidase-like 2B抗体
    参阅全部 Signal peptide peptidase-like 2B 一抗
  • 描述
    兔多克隆抗体to Signal肽peptidase-like 2B
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 100 - 200 of Human Signal peptide peptidase-like 2B.

    (Peptide available as ab43855.)

  • 阳性对照
    • This antibody gave a positive signal in WI38 Whole Cell Lysate, Human Thymus Tissue Lysate and Human Brain Tissue Lysate (data not shown).

性能

应用

Our Abpromise guarantee covers the use of ab43856 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 65 kDa).

靶标

  • 相关性The SPPLs are a group of aspartic proteases that are responsible for proteolysis of type II membrane-anchored signalling factors. SPPL2b, unlike other SPPL family members is found in endosomes/lysosomes, and not the endoplasmic reticulum, and has a role in catalysing intramembrane cleavage of tumour necrosis factor alpha (TNFalpha).
  • 细胞定位Membrane; multi-pass membrane protein of endosomes/lysosomes.
  • 数据库链接
  • 别名
    • IMP4 antibody
    • Intramembrane protease 4 antibody
    • Protein SPP-like 2B antibody
    • SPPL2B antibody

Anti-Signal peptide peptidase-like 2B antibody 图像

  • All lanes : Anti-Signal peptide peptidase-like 2B antibody (ab43856) at 1 µg/ml

    Lane 1 : WI-38 whole cell lysate (ab3960)
    Lane 2 : Human thymus tissue lysate - total protein (ab30146)

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

    Performed under reducing conditions.

    Predicted band size : 65 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)

Anti-Signal peptide peptidase-like 2B antibody (ab43856)参考文献

ab43856 has not yet been referenced specifically in any publications.

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