概述

  • 产品名称Anti-SIGLECL1抗体
    参阅全部 SIGLECL1 一抗
  • 描述
    兔多克隆抗体to SIGLECL1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 183-374 of Human SIGLECL1.

  • 阳性对照
    • MCF7 whole cell lysate; NT2D1, IMR32 and U87-MG cell lysates

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 20% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab106537 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 65 kDa.

靶标

  • 功能Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
  • 组织特异性Isoform Short is highly expressed in spleen, small intestine and adrenal gland; it is lower expressed in thyroid, placenta, brain, stomach, bone marrow, spinal chord and breast. Isoform Long is highly expressed in spleen, small intestine and bone marrow; it is lower expressed in thyroid, placenta, thymus, trachea, stomach, lung, adrenal gland, fetal brain and testis.
  • 序列相似性Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 2 Ig-like V-type (immunoglobulin-like) domains.
  • 结构域Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ38600 antibody
    • S2V antibody
    • sialic acid binding Ig-like lectin 12 (gene/pseudogene) antibody
    • Sialic acid-binding Ig-like lectin 12 antibody
    • Sialic acid-binding Ig-like lectin-like 1 antibody
    • Sialic acid-binding immunoglobulin-like lectins antibody
    • SIG12_HUMAN antibody
    • Siglec-12 antibody
    • Siglec-L1 antibody
    • SIGLEC-like 1 antibody
    • SIGLEC-like gene antibody
    • SIGLEC-like protein 1 antibody
    • Siglec-XII antibody
    • Siglec12 antibody
    • SLG antibody
    see all

Anti-SIGLECL1 antibody 图像

  • Anti-SIGLECL1 antibody (ab106537) at 1/2000 dilution + MCF7 whole cell lysate at 30 µg

    Predicted band size : 65 kDa

Anti-SIGLECL1 antibody (ab106537)参考文献

ab106537 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab106537.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"