概述

  • 产品名称Anti-SIGLEC8抗体
    参阅全部 SIGLEC8 一抗
  • 描述
    山羊多克隆抗体to SIGLEC8
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide:

    C-SYKSQLNYKTKQ

    , corresponding to internal sequence amino acids 134-145 of Human SIGLEC8 (NP_055257.2)

  • 阳性对照
    • MOLT4 cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab79285 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明Peptide ELISA: Antibody detection limit dilution 1/32000.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 54 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
    • 组织特异性Expressed specifically on eosinophils.
    • 序列相似性Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
      Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • 结构域Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CD329 antigen antibody
      • CDw329 antibody
      • SAF 2 antibody
      • SAF-2 antibody
      • SAF2 antibody
      • Sialic acid binding Ig like lectin 8 antibody
      • Sialic acid-binding Ig-like lectin 8 antibody
      • Sialoadhesin family member 2 antibody
      • SIGL8_HUMAN antibody
      • Siglec 8 antibody
      • Siglec-8 antibody
      • SIGLEC8 antibody
      • SIGLEC8L antibody
      see all

    Anti-SIGLEC8 antibody 图像

    Anti-SIGLEC8 antibody (ab79285)参考文献

    ab79285 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab79285.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"