概述

  • 产品名称Anti-SIGLEC14抗体[MM0550-4G4]
    参阅全部 SIGLEC14 一抗
  • 描述
    小鼠单克隆抗体[MM0550-4G4] to SIGLEC14
  • 特异性This antibody is known to show cross reactivity to Siglec-5
  • 经测试应用适用于: WB, Neutralisingmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment of Human SIGLEC14 extracellular domain.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and 0.2 µm filtered.
  • 克隆单克隆
  • 克隆编号MM0550-4G4
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab89482 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评��� 说明
WB 1/500 - 1/1000. Predicted molecular weight: 44 kDa.
Neutralising Use at an assay dependent dilution.

靶标

  • 功能Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors.
  • 组织特异性Mainly expressed in hematopoietic tissues including bone marrow, spleen and fetal liver. Also detected in lung and testis.
  • 序列相似性Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Sialic acid binding Ig like lectin 14 antibody
    • Sialic acid-binding Ig-like lectin 14 antibody
    • SIG14_HUMAN antibody
    • Siglec 14 antibody
    • Siglec-14 antibody
    • SIGLEC14 antibody
    see all

Anti-SIGLEC14 antibody [MM0550-4G4] (ab89482)参考文献

This product has been referenced in:
  • Brazil JC  et al. a3/4 Fucosyltransferase 3-dependent synthesis of Sialyl Lewis A on CD44 variant containing exon 6 mediates polymorphonuclear leukocyte detachment from intestinal epithelium during transepithelial migration. J Immunol 191:4804-17 (2013). Read more (PubMed: 24068663) »

See 1 Publication for this product

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