概述

  • 产品名称
    Anti-SIGLEC14抗体[MM0550-4G4]
    参阅全部 SIGLEC14 一抗
  • 描述
    小鼠单克隆抗体[MM0550-4G4] to SIGLEC14
  • 特异性
    This antibody is known to show cross reactivity to Siglec-5
  • 经测试应用
    适用于: WB, Neutralisingmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment of Human SIGLEC14 extracellular domain.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 纯化说明
    The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and 0.2 µm filtered.
  • 克隆
    单克隆
  • 克隆编号
    MM0550-4G4
  • 同种型
    IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab89482 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 44 kDa.
Neutralising Use at an assay dependent dilution.

靶标

  • 功能
    Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors.
  • 组织特异性
    Mainly expressed in hematopoietic tissues including bone marrow, spleen and fetal liver. Also detected in lung and testis.
  • 序列相似性
    Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Sialic acid binding Ig like lectin 14 antibody
    • Sialic acid-binding Ig-like lectin 14 antibody
    • SIG14_HUMAN antibody
    • Siglec 14 antibody
    • Siglec-14 antibody
    • SIGLEC14 antibody
    see all

实验方案

文献

This product has been referenced in:
  • Brazil JC  et al. a3/4 Fucosyltransferase 3-dependent synthesis of Sialyl Lewis A on CD44 variant containing exon 6 mediates polymorphonuclear leukocyte detachment from intestinal epithelium during transepithelial migration. J Immunol 191:4804-17 (2013). Read more (PubMed: 24068663) »

See 1 Publication for this product

客户评价及客户问答

There are currently no Customer reviews or Questions for ab89482.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册