Anti-Sialyl Tn抗体[STn 219], prediluted (ab76755)

概述

  • 产品名称Anti-Sialyl Tn抗体[STn 219], prediluted
    参阅全部 Sialyl Tn 一抗
  • 描述
    小鼠单克隆抗体[STn 219] to Sialyl Tn, prediluted
  • 经测试应用适用于: IHC-P, IHC-Frmore details
  • 种属反应性
    与反应: Sheep, Human
  • 免疫原

    Ovine submaxillary mucin (OSM)

  • 表位NeuAc alpha GalNacOSer/Thr
  • 阳性对照
    • Human gastrointestinal tumor, prostate and ovary carcinomas.

性能

应用

Our Abpromise guarantee covers the use of ab76755 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
IHC-Fr
  • 应用说明IHC-P: Ready to use.
    IHC-Fr: Ready to use.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Sialyl-Tn is a carbohydrate antigen overexpressed in several epithelial cancers including breast cancer, and usually associated with poor prognosis. Sialyl-Tn is synthesized by a CMP-Neu5Ac: GalNAc alpha2,6-sialyltransferase: ST6GalNAc I, which catalyzes the transfer of a sialic acid residue in alpha2,6-linkage to the GalNAcalpha1-O-Ser/Thr structure. The resulting disaccharide (Neu5Acalpha2-6GalNAcalpha1-O-Ser/Thr) cannot be further elongated and sialyl-Tn expression results therefore in a shortening of the O-glycan chains
    • 别名
      • CD175s antibody
      • Sialosyl Tn antibody
      • sTn antibody

    Anti-Sialyl Tn antibody [STn 219], prediluted (ab76755)参考文献

    ab76755 has not yet been referenced specifically in any publications.

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