Anti-SHPRH抗体[2994C1a] (ab84856)

概述

  • 产品名称
    Anti-SHPRH抗体[2994C1a]
    参阅全部 SHPRH 一抗
  • 描述
    小鼠单克隆抗体[2994C1a] to SHPRH
  • 经测试应用
    适用于: WB, Dot blotmore details
  • 种属反应性
    与反应: Recombinant fragment
    预测可用于: Human
  • 免疫原

    Recombinant fragment derived from the central region of Human SHPRH

性能

应用

Our Abpromise guarantee covers the use of ab84856 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 193 kDa.
Dot blot Use at an assay dependent dilution.

靶标

  • 功能
    E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'.
  • 组织特异性
    Broadly expressed.
  • 通路
    Protein modification; protein ubiquitination.
  • 序列相似性
    Belongs to the SNF2/RAD54 helicase family.
    Contains 1 H15 (linker histone H1/H5 globular) domain.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.
    Contains 1 PHD-type zinc finger.
    Contains 1 RING-type zinc finger.
  • 结构域
    The RING finger mediates E3 ubiquitin ligase activity.
  • Information by UniProt
  • 数据库链接
  • 别名
    • bA545I5.2 antibody
    • E3 ubiquitin-protein ligase SHPRH antibody
    • FLJ27258 antibody
    • FLJ37625 antibody
    • FLJ45012 antibody
    • FLJ90837 antibody
    • histone-linker antibody
    • KIAA2023 antibody
    • MGC134886 antibody
    • PHD and RING finger domain-containing helicase antibody
    • Shprh antibody
    • SHPRH_HUMAN antibody
    • SNF2 antibody
    • SNF2 histone linker PHD RING helicase antibody
    see all

图片

  • Anti-SHPRH antibody [2994C1a] (ab84856) + immunogen (recombinant fragment of Human SHPRH)

    Predicted band size : 193 kDa

实验方案

文献

ab84856 has not yet been referenced specifically in any publications.

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