概述

  • 产品名称
  • 描述
    兔多克隆抗体to SHC3
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within the internal sequence amino acids 359-408 (RLKPRPHAPD TAQFAGKEQT YYQGRHLGDT FGEDWQQTPL RQGSSDIYST) of Human SHC3 (NP_058544).

  • 阳性对照
    • HepG2 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab97972 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 64 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
  • 组织特异性
    Mainly expressed in brain. Hardly detectable in other tissues, except in pancreas. Highly expressed in the cerebral cortex, frontal and temporal lobes, occipital pole, hippocampus, caudate nucleus and amygdala. Expressed at low level in the cerebellum, medulla and spinal cord.
  • 序列相似性
    Contains 1 PID domain.
    Contains 1 SH2 domain.
  • 翻译后修饰
    Tyrosine phosphorylated.
  • Information by UniProt
  • 数据库链接
  • 别名
    • N SHC antibody
    • N-Shc antibody
    • Neuronal Shc antibody
    • NSHC antibody
    • Protein Rai antibody
    • Rai antibody
    • SH2 domain protein C3 antibody
    • SHC (Src homology 2 domain containing) transforming protein 3 antibody
    • SHC adaptor protein 3 antibody
    • SHC protein C antibody
    • SHC-like protein, neuronal antibody
    • SHC-transforming protein 3 antibody
    • SHC-transforming protein C antibody
    • Shc3 antibody
    • Shc3 p51 antibody
    • SHC3_HUMAN antibody
    • SHCC antibody
    • Src homology 2 domain-containing transforming protein antibody
    • Src homology 2 domain-containing-transforming protein C3 antibody
    see all

Anti-SHC3 antibody 图像

  • Anti-SHC3 antibody (ab97972) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 64 kDa

实验方案

Anti-SHC3 antibody (ab97972)参考文献

ab97972 has not yet been referenced specifically in any publications.

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