概述

  • 产品名称Anti-SHC3抗体
    参阅全部 SHC3 一抗
  • 描述
    小鼠多克隆抗体to SHC3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length human protein (NP_058544.2)

  • 阳性对照
    • SHC3 transfected 293T cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab69355 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 70 kDa (predicted molecular weight: 64 kDa).

靶标

  • 功能Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
  • 组织特异性Mainly expressed in brain. Hardly detectable in other tissues, except in pancreas. Highly expressed in the cerebral cortex, frontal and temporal lobes, occipital pole, hippocampus, caudate nucleus and amygdala. Expressed at low level in the cerebellum, medulla and spinal cord.
  • 序列相似性Contains 1 PID domain.
    Contains 1 SH2 domain.
  • 翻译后修饰Tyrosine phosphorylated.
  • Information by UniProt
  • 数据库链接
  • 别名
    • N SHC antibody
    • N-Shc antibody
    • Neuronal Shc antibody
    • NSHC antibody
    • Protein Rai antibody
    • Rai antibody
    • SH2 domain protein C3 antibody
    • SHC (Src homology 2 domain containing) transforming protein 3 antibody
    • SHC protein C antibody
    • SHC-like protein, neuronal antibody
    • SHC-transforming protein 3 antibody
    • SHC-transforming protein C antibody
    • Shc3 antibody
    • SHC3_HUMAN antibody
    • SHCC antibody
    • Src homology 2 domain-containing transforming protein antibody
    • Src homology 2 domain-containing-transforming protein C3 antibody
    see all

Anti-SHC3 antibody 图像

  • All lanes : Anti-SHC3 antibody (ab69355) at 1/500 dilution

    Lane 1 : SHC3 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP conjugated at 1/2500 dilution

    Predicted band size : 64 kDa
    Observed band size : 70 kDa (why is the actual band size different from the predicted?)

Anti-SHC3 antibody (ab69355)参考文献

ab69355 has not yet been referenced specifically in any publications.

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