概述

  • 产品名称Anti-SHANK1抗体
    参阅全部 SHANK1 一抗
  • 描述
    兔多克隆抗体to SHANK1
  • 特异性Reacts with residues [ERLLREYPQSFEKGV] of the N terminus of the SHANK1 protein.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide:

    SGPIYPGLFDIRSS

    of Rat SHANK1.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液PBS with 0.02% sodium azide
  • Concentration information loading...
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab3897 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000.

靶标

  • 功能Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.
  • 组织特异性Expressed in brain particularly in the amygdala, hippocampus, substantia nigra and thalamus. Isoform 2 seems to be expressed ubiquitously.
  • 序列相似性Belongs to the SHANK family.
    Contains 6 ANK repeats.
    Contains 1 PDZ (DHR) domain.
    Contains 1 SAM (sterile alpha motif) domain.
    Contains 1 SH3 domain.
  • 细胞定位Cytoplasm. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse. Postsynaptic density of neuronal cells.
  • Information by UniProt
  • 数据库链接
  • 别名
    • GKAP/SAPAP interacting protein antibody
    • OTTHUMP00000174437 antibody
    • SH3 and multiple ankyrin repeat domains 1 antibody
    • SH3 and multiple ankyrin repeat domains protein 1 antibody
    • SH3/ankyrin domain gene 1 antibody
    • SHAN1_HUMAN antibody
    • SHANK 1 antibody
    • Shank1 antibody
    • Shank1a antibody
    • Somatostatin receptor interacting protein antibody
    • Somatostatin receptor-interacting protein antibody
    • SPANK 1 antibody
    • SPANK1 antibody
    • SSTR interacting protein antibody
    • SSTR-interacting protein antibody
    • SSTRIP antibody
    • Synamon antibody
    see all

Anti-SHANK1 antibody (ab3897)参考文献

This product has been referenced in:

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab3897.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"