概述

  • 产品名称Anti-SH3BP2抗体
    参阅全部 SH3BP2 一抗
  • 描述
    小鼠单克隆抗体to SH3BP2
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 452-561 of Human SH3BP2

性能

应用

Our Abpromise guarantee covers the use of ab55696 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 62 kDa.
ICC/IF Use a concentration of 10 µg/ml.

靶标

  • 功能Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. Binds to phosphatidylinositols; linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylation dependent mechanism.
  • 组织特异性Expressed in a variety of tissues including lung, liver, skeletal muscle, kidney and pancreas.
  • 疾病相关Defects in SH3BP2 are the cause of cherubism (CRBM) [MIM:118400]. CRBM is an autosomal dominant inherited syndrome characterized by excessive bone degradation of the upper and lower jaws, which often begins around three years of age. It is followed by development of fibrous tissue masses, which causes a characteristic facial swelling.
  • 序列相似性Contains 1 PH domain.
    Contains 1 SH2 domain.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 3BP-2 antibody
    • 3BP2 antibody
    • 3BP2_HUMAN antibody
    • Abl SH3 binding protein 2 antibody
    • Cherubism antibody
    • CRBM antibody
    • CRPM antibody
    • FLJ42079 antibody
    • FLJ54978 antibody
    • RES4-23 antibody
    • SH3 domain binding protein 2 antibody
    • SH3 domain-binding protein 2 antibody
    • Sh3bp2 antibody
    • TNFAIP3 interacting protein 2 antibody
    see all

Anti-SH3BP2 antibody 图像



  • Predicted band size : 62 kDa
    SH3BP2 antibody (ab55696) at 1ug/lane + A-431 cell lysate at 25ug/lane.
  • ab55696 at 10 ug/ml staining SH3BP2 in human Hella cells by Immunocytochemistry/ Immunofluorescence.

Anti-SH3BP2 antibody (ab55696)参考文献

ab55696 has not yet been referenced specifically in any publications.

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