Anti-SH3 containing Grb 2 like 1 protein抗体(ab86605)

概述

  • 产品名称Anti-SH3 containing Grb 2 like 1 protein抗体
    参阅全部 SH3 containing Grb 2 like 1 protein 一抗
  • 描述
    兔多克隆抗体to SH3 containing Grb 2 like 1 protein
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Human
    预测可用于: Dog, Chimpanzee, Ferret, Rhesus monkey, Orangutan
  • 免疫原

    Synthetic peptide, corresponding to a region between residues 225 and 275 of human SH3 containing Grb 2 like 1 protein (NP_003016.1)

  • 阳性对照
    • HeLa whole cell lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab86605 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/2000 - 1/10000. Detects a band of approximately 41 kDa (predicted molecular weight: 41 kDa).
IP Use at 2-5 µg/mg of lysate.

靶标

  • 功能Implicated in endocytosis. May recruit other proteins to membranes with high curvature.
  • 组织特异性Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus.
  • 疾病相关Note=In some cases of acute leukemia, a translocation results in the formation of a MLL-EEN fusion gene.
  • 序列相似性Belongs to the endophilin family.
    Contains 1 BAR domain.
    Contains 1 SH3 domain.
  • 结构域An N-terminal amphipathic helix, the BAR domain and a second amphipathic helix inserted into helix 1 of the BAR domain (N-BAR domain) induce membrane curvature and bind curved membranes.
  • 细胞定位Cytoplasm. Early endosome membrane. Associated with postsynaptic endosomes in hippocampal neurons.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CNSA1 antibody
    • EEN antibody
    • EEN fusion partner of MLL antibody
    • Endophilin-2 antibody
    • Endophilin-A2 antibody
    • Extra 11 19 leukemia fusion gene antibody
    • Extra eleven-nineteen leukemia fusion gene protein antibody
    • Fusion partner of MLL antibody
    • MGC111371 antibody
    • SH3 containing Grb 2 like 1 protein antibody
    • SH3 containing protein EEN antibody
    • SH3 domain GRB2 like 1 antibody
    • SH3 domain protein 2B antibody
    • SH3 domain-containing GRB2-like protein 1 antibody
    • SH3D2B antibody
    • SH3G1_HUMAN antibody
    • Sh3gl1 antibody
    • SH3P8 antibody
    see all

Anti-SH3 containing Grb 2 like 1 protein antibody 图像

  • All lanes : Anti-SH3 containing Grb 2 like 1 protein antibody (ab86605) at 0.04 µg/ml

    Lane 1 : HeLa whole cell lysate at 50 µg
    Lane 2 : HeLa whole cell lysate at 15 µg
    Lane 3 : HeLa whole cell lysate at 5 µg


    Predicted band size : 41 kDa


    Exposure time : 30 seconds
  • Detection of SH3 containing Grb 2 like 1 protein by Western Blot of Immunprecipitate.
    ab86605 at 1µg/ml staining SH3 containing Grb 2 like 1 protein in HeLa whole cell lysate immunoprecipitated using ab86605 at 3µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
    Detection: Chemiluminescence with exposure time of 10 seconds.

Anti-SH3 containing Grb 2 like 1 protein antibody (ab86605)参考文献

ab86605 has not yet been referenced specifically in any publications.

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