概述

  • 产品名称Anti-SH2D4A抗体
    参阅全部 SH2D4A 一抗
  • 描述
    兔多克隆抗体to SH2D4A
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length protein, corresponding to amino acids 1-454 of Human SH2D4A (NP_071354.2).

  • 阳性对照
    • Human pancreas and SH2D4A transfected 293T cell line lysate

性能

应用

Our Abpromise guarantee covers the use of ab103166 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 53 kDa.
IHC-P 1/200. PubMed: 24315626

靶标

  • 功能Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.
  • 组织特异性Ubiquitously expressed. Aberrantly expressed in some cancers.
  • 序列相似性Contains 1 SH2 domain.
  • 细胞定位Cytoplasm. Located at podocyte foot processes.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ20967 antibody
    • PPP1R38 antibody
    • Protein phosphatase 1 regulatory subunit 38 antibody
    • Protein SH antibody
    • Protein SH(2)A antibody
    • Protein SH2A antibody
    • SH2 domain containing 4A antibody
    • SH2 domain containing protein 4A antibody
    • SH2 domain-containing protein 4A antibody
    • SH24A_HUMAN antibody
    • SH2A antibody
    • Sh2d4a antibody
    see all

Anti-SH2D4A antibody 图像

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of normal liver (left) and hepatocellular carcinoma (right) labelling SH2D4A with ab103166 at 1/200. Magnification: 400X. Representative pictures of different protein levels for SH2D4A.

  • Anti-SH2D4A antibody (ab103166) at 1/500 dilution + Human pancreas tissue lysate at 50 µg

    Predicted band size : 53 kDa
  • All lanes : Anti-SH2D4A antibody (ab103166) at 1/500 dilution

    Lane 1 : SH2D4A transfected 293T cell line lysate
    Lane 2 : Non transfected lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 53 kDa

Anti-SH2D4A antibody (ab103166)参考文献

This product has been referenced in:
  • Quagliata L  et al. SH2D4A is frequently downregulated in hepatocellular carcinoma and cirrhotic nodules. Eur J Cancer 50:731-8 (2014). IHC-P ; Human . Read more (PubMed: 24315626) »

See 1 Publication for this product

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