概述

  • 产品名称Anti-SH2D2A抗体
    参阅全部 SH2D2A 一抗
  • 描述
    兔多克隆抗体to SH2D2A
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 94-124 of Human SH2D2A.

  • 阳性对照
    • MDA-MB435 cell line lysates.

性能

应用

Our Abpromise guarantee covers the use of ab103772 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 43 kDa.

靶标

  • 功能Could be a T-cell-specific adapter protein involved in the control of T-cell activation. May play a role in the CD4-p56-LCK-dependent signal transduction pathway. Could also play an important role in normal and pathological angiogenesis. Could be an adapter protein that facilitates and regulates interaction of KDR with effector proteins important to endothelial cell survival and proliferation.
  • 组织特异性Expression limited to tissues of the immune system and, in particular, activated T-cells. Expressed in peripheral blood leukocytes, thymus and spleen. Much lower expression or undetectable, in brain, placenta, skeletal muscle, prostate, testis, ovary, small intestine, and colon. Expressed at low levels in unstimulated T-cells, but not expressed in normal resting or activated B-cells. According to PubMed:10692392, expression is not restricted to activated T-cells, but strongly expressed in blood cell lineages, the endothelium and other cell and tissue types, such as heart, lung, and liver.
  • 序列相似性Contains 1 SH2 domain.
  • 翻译后修饰Phosphorylated on tyrosine residues.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • F2771 antibody
    • SCAP antibody
    • SH2 domain containing adapter protein antibody
    • SH2 domain containing protein 2A antibody
    • SH2 domain protein 2A antibody
    • SH2 domain-containing adapter protein antibody
    • SH2 domain-containing protein 2A antibody
    • SH22A_HUMAN antibody
    • Sh2d2a antibody
    • T cell specific adapter protein antibody
    • T cell specific adapter protein TSAd antibody
    • T cell specific adpater protein TSAd antibody
    • T cell-specific adapter protein antibody
    • T lymphocyte specific adaptor protein antibody
    • TSAd antibody
    • VEGF receptor associated protein antibody
    • VEGF receptor-associated protein antibody
    • VRAP antibody
    see all

Anti-SH2D2A antibody 图像

  • Anti-SH2D2A antibody (ab103772) at 1/100 dilution + MDA-MB435 cell line lysates at 35 µg

    Predicted band size : 43 kDa

Anti-SH2D2A antibody (ab103772)参考文献

ab103772 has not yet been referenced specifically in any publications.

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