概述

  • 产品名称Anti-SGLT1抗体
    参阅全部 SGLT1 一抗
  • 描述
    兔多克隆抗体to SGLT1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to an area surrounding amino acid 594 of Human SGLT1.

  • 阳性对照
    • Jurkat cell lysate

性能

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应用

Our Abpromise guarantee covers the use of ab97682 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 - 4 µg/ml. Detects a band of approximately 73 kDa (predicted molecular weight: 73 kDa). A ~50 kDa cleavage fragment can also be detected in Jurkat cell lysate.

靶标

  • 功能Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.
  • 组织特异性Expressed mainly in intestine and kidney.
  • 疾病相关Congenital glucose/galactose malabsorption
  • 序列相似性Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  • 翻译后修饰N-glycosylation is not necessary for the cotransporter function.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • D22S675 antibody
    • High affinity sodium glucose cotransporter 1 antibody
    • High affinity sodium glucose cotransporter antibody
    • High affinity sodium-glucose cotransporter antibody
    • Human Na+/glucose cotransporter 1 antibody
    • Na(+)/glucose cotransporter 1 antibody
    • Na+/glucose cotransporter 1 antibody
    • NAGT antibody
    • SC5A1_HUMAN antibody
    • SGLT 1 antibody
    • SGLT1 antibody
    • SLC5A1 antibody
    • Sodium glucose cotransporter 1 antibody
    • Sodium/glucose cotransporter 1 antibody
    • Solute carrier family 5 (sodium/glucose cotransporter) member 1 antibody
    • Solute carrier family 5 member 1 antibody
    see all

Anti-SGLT1 antibody 图像

  • Anti-SGLT1 antibody (ab97682) at 4 µg/ml + Jurkat cell lysate

    Predicted band size : 73 kDa

Anti-SGLT1 antibody (ab97682)参考文献

ab97682 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Loading amount 100 µg
Gel Running Conditions Reduced Denaturing (SDS-acrylamide 10%)
Sample Human Cell lysate - whole cell (enteroendocrine cell)
Specification enteroendocrine cell
Blocking step Milk as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 28°C
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提交于 Sep 17 2014

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"