概述

  • 产品名称Anti-SGEF抗体
    参阅全部 SGEF 一抗
  • 描述
    兔多克隆抗体to SGEF
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Cow, Cat, Pig, Saccharomyces cerevisiae
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 1-50 (MDGESEVDFSSNSITPLWRRRSIPQPHQVLGRSKPRPQSYQSPNGLLIT D) of Human SGEF (NP_056410).

  • 阳性对照
    • OVCAR-3 cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab98848 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 97 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.
  • 组织特异性Isoform 1 is broadly expressed, with highest levels in liver (at protein level). Certain mRNA species appear to be specifically expressed in prostate and liver.
  • 序列相似性Contains 1 DH (DBL-homology) domain.
    Contains 1 PH domain.
    Contains 1 SH3 domain.
  • 细胞定位Cell projection, ruffle.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ARHGEF26 antibody
    • ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 antibody
    • ARHGQ_HUMAN antibody
    • CSGEF antibody
    • DKFZp434D146 antibody
    • HMFN1864 antibody
    • Rho guanine nucleotide exchange factor 26 antibody
    • SH3 domain-containing guanine exchange factor antibody
    see all

Anti-SGEF antibody 图像

  • Anti-SGEF antibody (ab98848) at 1 µg/ml + OVCAR-3 cell lysate at 10 µg

    Predicted band size : 97 kDa

Anti-SGEF antibody (ab98848)参考文献

ab98848 has not yet been referenced specifically in any publications.

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