Anti-SFRS9抗体(ab88749)

概述

  • 产品名称Anti-SFRS9抗体
    参阅全部 SFRS9 一抗
  • 描述
    小鼠单克隆抗体to SFRS9
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Cow, Dog, Pig, Chimpanzee
  • 免疫原

    Recombinant fragment: MSGWADERGG EGDGRIYVGN LPTDVREKDL EDLFYKYGRI REIELKNRHG LVPFAFVRFE DPRDAEDAIY GRNGYDYGQC RLRVEFPRTY GGRGGWPRGG , corresponding to N terminal amino acids 1-101 of Human SFRS9 (NP_003760) linked to a proprietary tag.

  • 阳性对照
    • Raw 264.7 cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 1 x PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆单克隆
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab88749 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 26 kDa.
ELISA Use at an assay dependent dilution.

靶标

  • 功能Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10.
  • 组织特异性Expressed at high levels in the heart, kidney, pancreas and placenta, and at lower levels in the brain, liver, lung and skeletal muscle.
  • 序列相似性Belongs to the splicing factor SR family.
    Contains 2 RRM (RNA recognition motif) domains.
  • 翻译后修饰Extensively phosphorylated on serine residues in the RS domain.
  • 细胞定位Nucleus. Cellular stresses such as heat shock may induce localization to discrete nuclear bodies termed SAM68 nuclear bodies (SNBs), HAP bodies, or stress bodies. Numerous splicing factors including SRSF1/SFRS1/SF2, SRSF7/SFRS7, SAFB and KHDRBS1/SAM68 accumulate at these structures, which may participate in the post-transcriptional regulation of mRNAs in stressed cells.
  • Information by UniProt
  • 数据库链接
  • 别名
    • arginine/serine-rich 9 antibody
    • Pre mRNA splicing factor SRp30C antibody
    • Pre-mRNA-splicing factor SRp30C antibody
    • Serine/arginine-rich splicing factor 9 antibody
    • SFRS 9 antibody
    • Splicing factor antibody
    • Splicing factor arginine/serine rich 9 antibody
    • splicing factor, arginine/serine-rich 9 antibody
    • splicing factor, arginine/serine-rich, 30-KD, C antibody
    • SR splicing factor 9 antibody
    • SRP30C antibody
    • SRSF9 antibody
    • SRSF9_HUMAN antibody
    see all

Anti-SFRS9 antibody 图像

Anti-SFRS9 antibody (ab88749)参考文献

ab88749 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Mouse Cell lysate - whole cell (NSC34)
Loading amount 20 µg
Specification NSC34
Gel Running Conditions Reduced Denaturing (4-12% nupage gel)
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
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提交于 Feb 15 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"