概述

  • 产品名称Anti-SFRP2抗体
    参阅全部 SFRP2 一抗
  • 描述
    山羊多克隆抗体to SFRP2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Chicken, Cow, Dog, Chimpanzee, Zebrafish
  • 免疫原

    Synthetic peptide:

    C-KRWQKGQREFKR

    , corresponding to C terminal amino acids 274-285 of Human SFRP2 (NP_003004.1)

  • 阳性对照
    • Human Duodenum lysate.

性能

应用

Our Abpromise guarantee covers the use of ab77618 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 33 kDa).

靶标

  • 功能Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.
  • 组织特异性Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon.
  • 序列相似性Belongs to the secreted frizzled-related protein (sFRP) family.
    Contains 1 FZ (frizzled) domain.
    Contains 1 NTR domain.
  • 结构域The FZ domain is involved in binding with Wnt ligands.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AI851596 antibody
    • Frizzled related protein 2 antibody
    • FRP 2 antibody
    • FRP-2 antibody
    • FRP2 antibody
    • MGC128911 antibody
    • MGC153618 antibody
    • MGC53344 antibody
    • SARP 1 antibody
    • SARP-1 antibody
    • SARP1 antibody
    • SDF 5 antibody
    • SDF5 antibody
    • Secreted apoptosis related protein 1 antibody
    • Secreted apoptosis-related protein 1 antibody
    • Secreted frizzled related protein 2 antibody
    • Secreted frizzled-related protein 2 antibody
    • sFRP 2 antibody
    • sFRP-2 antibody
    • SFRP2 antibody
    • Sfrp2 protein antibody
    • SFRP2_HUMAN antibody
    see all

Anti-SFRP2 antibody 图像

Anti-SFRP2 antibody (ab77618)参考文献

This product has been referenced in:
  • Yamamura S  et al. Oncogenic functions of secreted Frizzled-related protein 2 in human renal cancer. Mol Cancer Ther 9:1680-7 (2010). WB ; Human . Read more (PubMed: 20501806) »

See 1 Publication for this product

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