概述

  • 产品名称Anti-SF3B3抗体
    参阅全部 SF3B3 一抗
  • 描述
    兔多克隆抗体to SF3B3
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Dog, Turkey, Chimpanzee, Zebrafish, Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis
  • 免疫原

    Synthetic peptide corresponding to a region between residues 1167 and 1217 of Human SF3B3 (NP_036558.3).

  • 阳性对照
    • Human breast carcinoma, colon carcinoma, non-small cell lung cancer, ovarian carcinoma, prostate carcinoma or stomach adenocarcinoma tissue. Mouse colon carcinoma CT26, hybridoma tumor, renal cell carcinoma or teratoma tissue.
  • 常规说明Shelf Life: 1 year from date of receipt

性能

应用

Our Abpromise guarantee covers the use of ab124658 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
  • 序列相似性Belongs to the RSE1 family.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • KIAA0017 antibody
    • Pre mRNA splicing factor SF3b 130 kDa subunit antibody
    • Pre-mRNA-splicing factor SF3b 130 kDa subunit antibody
    • RSE1 antibody
    • SAP 130 antibody
    • SAP130 antibody
    • SF3b130 antibody
    • SF3B3 antibody
    • SF3B3_HUMAN antibody
    • Spliceosome associated protein 130 antibody
    • Spliceosome-associated protein 130 antibody
    • Splicing factor 3b subunit 3 130kD antibody
    • Splicing factor 3B subunit 3 antibody
    • STAF130 antibody
    see all

Anti-SF3B3 antibody 图像

  • ab124658, at 1/500 dilution, staining SF3B3 in Formalin-fixed Paraffin-embedded Human ovarian carcinoma tissue, by Immunohistochemistry. Detection by DAB staining.
  • ab124658, at 1/100 dilution, staining SF3B3 in Formalin-fixed Paraffin-embedded Mouse renal cell carcinoma tissue, by Immunohistochemistry. Detection by DAB staining.

Anti-SF3B3 antibody (ab124658)参考文献

ab124658 has not yet been referenced specifically in any publications.

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