概述

  • 产品名称Anti-SF3B2抗体
    参阅全部 SF3B2 一抗
  • 描述
    小鼠单克隆抗体to SF3B2
  • 经测试应用适用于: WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Recombinant fragment: ISLGMPVGPN AHKVPPPWLI AMQRYGPPPS YPNLKIPGLN SPIPESCSFG YHAGG, corresponding to amino acids 592-646 of Human SF3B2

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab56800 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 98 kDa.
IHC-P Use a concentration of 6 µg/ml.
ICC/IF Use a concentration of 60 µg/ml.

靶标

  • 相关性SF3B2 is a subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. SF3B2 may also be involved in the assembly of the 'E' complex. It also belongs to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
  • 细胞定位Nuclear
  • 数据库链接
  • 别名
    • Pre mRNA splicing factor SF3b 145 kDa subunit antibody
    • SAP 145 antibody
    • SAP145 antibody
    • SF3b1 antibody
    • SF3B145 antibody
    • SF3b150 antibody
    • Spliceosome associated protein 145 antibody
    • Splicing factor 3b subunit 2 145kDa antibody
    • Splicing factor 3b subunit 2 antibody
    see all

Anti-SF3B2 antibody 图像

  • SF3B2 antibody (ab56800) used in immunohistochemistry at 6ug/ml on formalin fixed and paraffin embedded human kidney.


  • Predicted band size : 98 kDa
  • ab56800, at 60 µg/ml staining SF3B2 in HeLa Cells by immunocytochemistry.Immunofluorescence of ab56800 to SF3B2 on HeLa cell, performed with antibody concentration at 60 ug/ml.

Anti-SF3B2 antibody (ab56800)参考文献

This product has been referenced in:
  • Lin-Moshier Y  et al. Re-evaluation of the role of calcium homeostasis endoplasmic reticulum protein (CHERP) in cellular calcium signaling. J Biol Chem 288:355-67 (2013). WB . Read more (PubMed: 23148228) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"