概述

  • 产品名称Anti-SF3A1抗体
    参阅全部 SF3A1 一抗
  • 描述
    兔多克隆抗体to SF3A1
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rabbit, Horse, Cow, Dog, Ferret, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between amino acids 300 and 350 of Human SF3A1 (NP_005868.1).

  • 阳性对照
    • Human Anaplastic Thyroid Carcinoma, Bladder Cell Carcinoma, Breast Carcinoma, Colon Carcinoma, Linitis Plastica Stomach Cancer, Ovarian Carcinoma, Pancreatic Islet Cell Tumor, Small Cell Lung Cancer, Stomach Adenocarcinoma and Testicular Seminoma. Mouse Renal Cell Carcinoma and Teratoma.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab84698 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.
    • 组织特异性Ubiquitously expressed.
    • 序列相似性Contains 2 SURP motif repeats.
      Contains 1 ubiquitin-like domain.
    • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Pre mRNA processing 21 antibody
      • Pre mRNA splicing factor SF3a antibody
      • PRP21 antibody
      • PRPF21 antibody
      • SAP 114 antibody
      • SAP114 antibody
      • sf3a1 antibody
      • SF3A1_HUMAN antibody
      • SF3a120 antibody
      • Spliceosome associated protein 114 antibody
      • Spliceosome-associated protein 114 antibody
      • Splicing factor 3 subunit 1 antibody
      • Splicing factor 3a subunit 1 120kDa antibody
      • Splicing factor 3A subunit 1 antibody
      see all

    Anti-SF3A1 antibody 图像

    • ab84698, at 1/250 dilution, staining SF3A1 in formalin-fixed, paraffin-embedded human pancreatic islet cell tumor by Immunohistochemistry, using DAB staining.
    • ab84698, at 1/100 dilution, staining SF3A1 in formalin-fixed, paraffin-embedded mouse teratoma by Immunohistochemistry, using DAB staining.
    • ab84698, at 1/100 dilution, staining SF3A1 in formalin-fixed, paraffin-embedded human breast carcinoma by Immunohistochemistry using a Red fluorescent goat anti-rabbit IgG highly cross adsorbed Hilyte PlusTM 555 secondary antibody at a dilution of 1/100.

    Anti-SF3A1 antibody (ab84698)参考文献

    ab84698 has not yet been referenced specifically in any publications.

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