Anti-Serum Response Factor SRF抗体(ab79378)

概述

• 产品名称
  Anti-Serum Response Factor SRF抗体
  参阅全部 Serum Response Factor SRF 一抗
• 描述
  兔多克隆抗体to Serum Response Factor SRF
• 特异性
  This antibody detects endogenous levels of total Serum Response Factor SRF protein.
• 经测试应用
  适用于: ELISA, WBmore details
• 种属反应性
  与反应: Human
  预测可用于: Mouse
• 免疫原

  Synthesized non phosphopeptide derived from human Serum Response Factor SRF around the phosphorylation site of threonine 159 (R-Y-T^P-T-F)

• 阳性对照
  • Extracts from HeLa cells.

性能

• 形式
  Liquid
• 存放说明
  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• 存储溶液
  Preservative: 0.02% Sodium Azide
  Constituents: 50% Glycerol, PBS (without Mg²⁺ and Ca²⁺), 150mM Sodium chloride, pH 7.4
• Concentration information loading...
• 纯度
  Immunogen affinity purified
• 纯化说明
  The antibody was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen.
• 克隆
  多克隆
• 同种型
  IgG
• 研究领域
  • Epigenetics and Nuclear Signaling
  • Transcription
  • Other factors

  • Stem Cells
  • Lineage Markers
  • Mesoderm

  • Cardiovascular
  • Heart
  • Cardiogenesis
  • Transcription factors/regulators

  • Developmental Biology
  • Lineage specification
  • Mesoderm

相关产品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

应用

靶标

• 功能
  SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Required for cardiac differentiation and maturation.
• 序列相似性
  Contains 1 MADS-box domain.
• 翻译后修饰
  Phosphorylated by PRKDC.
• 细胞定位
  Nucleus.

• Target information above from: UniProt accession P11831 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 6722 Human
  • Entrez Gene: 20807 Mouse
  • Omim: 600589 Human
  • SwissProt: P11831 Human
  • SwissProt: Q9JM73 Mouse
  • Unigene: 520140 Human
  • Unigene: 45044 Mouse
• 别名
  • c fos serum response element binding factor antibody
  • c fos serum response element binding transcription factor antibody
  • ELK3 antibody

  • ERP antibody
  • MCM 1 antibody
  • MCM1 antibody
  • OTTHUMP00000039820 antibody
  • SAP2 antibody
  • Serum response factor antibody
  • SRF antibody
  • SRF serum response factor c fos serum response element binding transcription factor antibody
  • SRF_HUMAN antibody

  see all

实验方案

• Western blot protocols