概述

  • 产品名称Anti-Serum Amyloid A抗体[Reu-86.2]
    参阅全部 Serum Amyloid A 一抗
  • 描述
    小鼠单克隆抗体[Reu-86.2] to Serum Amyloid A
  • 特异性The antibody reacts with AA-type Amyloid depositions.
  • 经测试应用适用于: IHC-Fr, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Human serum Amyloid A (Apo-SAA).

  • 阳性对照
    • Amyloid depositions (renal biopsy).
  • 常规说明


    Amyloidosis includes a family of diseases which have in common the extracellular deposition of ß-pleated fibrillar protein. Amyloidosis associated with chronic inflammatory conditions (AA-type) and Amyloidosis related to plasma cel dyscrasia (AL-type) are the most common, but the frequency of amyloidosis associated with chronic haemodialysis (B2M-type) is growing rapidly. Reu-86.2 can be used in routine diagnosis of amyloidosis both for detection of the AA-type as for the discimination from the other types of amyloidosis such as the B2M- and AL-type.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 纯度Tissue culture supernatant
  • Primary antibody说明Amyloidosis includes a family of diseases which have in common the extracellular deposition of ß-pleated fibrillar protein. Amyloidosis associated with chronic inflammatory conditions (AA-type) and Amyloidosis related to plasma cel dyscrasia (AL-type) are the most common, but the frequency of amyloidosis associated with chronic haemodialysis (B2M-type) is growing rapidly. Reu-86.2 can be used in routine diagnosis of amyloidosis both for detection of the AA-type as for the discimination from the other types of amyloidosis such as the B2M- and AL-type.
  • 克隆单克隆
  • 克隆编号Reu-86.2
  • 同种型IgG2a
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab8057 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.

靶标

  • 功能Major acute phase reactant. Apolipoprotein of the HDL complex.
  • 组织特异性Expressed by the liver; secreted in plasma.
  • 疾病相关Note=Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.
    Note=Elevated serum SSA protein levels may be associated with lung cancer.
  • 序列相似性Belongs to the SAA family.
  • 翻译后修饰This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Amyloid fibril protein AA antibody
    • Amyloid fibrils antibody
    • Amyloid protein A antibody
    • Fibrils antibody
    • MGC111216 antibody
    • OC antibody
    • PIG 4 antibody
    • PIG4 antibody
    • SAA 1 antibody
    • SAA 2 antibody
    • SAA antibody
    • SAA_HUMAN antibody
    • SAA1 antibody
    • SAA2 antibody
    • Serum amyloid A protein precursor antibody
    • Serum amyloid A1 isoform 1 antibody
    • Serum amyloid A1 isoform 2 antibody
    • Serum amyloid protein A(4-101) antibody
    • TP53I4 antibody
    • Tumor protein p53 inducible protein 4 antibody
    see all

Anti-Serum Amyloid A antibody [Reu-86.2] (ab8057)参考文献

This product has been referenced in:
  • Hazenberg BPC (Natvig JB Eds.) et al. Detection of Amyloid AA in rectal biopsies with a new monoclonal anti-human SAA antibody (Reu 86.2). Amyloid and Amyloidosis :809-812 (1991). Read more (PubMed: ) »

See 1 Publication for this product

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