Anti-Serum Amyloid A抗体[Reu-86.2] (ab8057)

概述

• 产品名称Anti-Serum Amyloid A抗体[Reu-86.2]
  参阅全部 Serum Amyloid A 一抗
• 描述
  小鼠单克隆抗体[Reu-86.2] to Serum Amyloid A
• 特异性The antibody reacts with AA-type Amyloid depositions.
• 经测试应用适用于: IHC-Fr, IHC-Pmore details
• 种属反应性
  与反应: Human
  
• 免疫原

  Human serum Amyloid A (Apo-SAA).

• 阳性对照
  • Amyloid depositions (renal biopsy).
• 常规说明

  
  

  Amyloidosis includes a family of diseases which have in common the extracellular deposition of ß-pleated fibrillar protein. Amyloidosis associated with chronic inflammatory conditions (AA-type) and Amyloidosis related to plasma cel dyscrasia (AL-type) are the most common, but the frequency of amyloidosis associated with chronic haemodialysis (B2M-type) is growing rapidly. Reu-86.2 can be used in routine diagnosis of amyloidosis both for detection of the AA-type as for the discimination from the other types of amyloidosis such as the B2M- and AL-type.

性能

• 形式Liquid
• 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
• 纯度Tissue culture supernatant
• Primary antibody说明Amyloidosis includes a family of diseases which have in common the extracellular deposition of ß-pleated fibrillar protein. Amyloidosis associated with chronic inflammatory conditions (AA-type) and Amyloidosis related to plasma cel dyscrasia (AL-type) are the most common, but the frequency of amyloidosis associated with chronic haemodialysis (B2M-type) is growing rapidly. Reu-86.2 can be used in routine diagnosis of amyloidosis both for detection of the AA-type as for the discimination from the other types of amyloidosis such as the B2M- and AL-type.
• 克隆单克隆
• 克隆编号Reu-86.2
• 同种型IgG2a
• 研究领域
  • Cardiovascular
  • Blood
  • Acute Phase Reactants

  • Cardiovascular
  • Blood
  • Serum Proteins

  • Cardiovascular
  • Lipids / Lipoproteins
  • Lipoproteins/Apolipoproteins
  • Lipoproteins

相关产品

• Compatible Secondaries
  • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
  • Goat Anti-Mouse IgG H&L (HRP) (ab205719)

应用

靶标

• 功能Major acute phase reactant. Apolipoprotein of the HDL complex.
• 组织特异性Expressed by the liver; secreted in plasma.
• 疾病相关Note=Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.
  Note=Elevated serum SSA protein levels may be associated with lung cancer.
• 序列相似性Belongs to the SAA family.
• 翻译后修饰This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end.
• 细胞定位Secreted.

• Target information above from: UniProt accession P02735 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 6288 Human
  • Entrez Gene: 6289 Human
  • Entrez Gene: 694827 Human
  • Omim: 104750 Human
  • SwissProt: P02735 Human
  • SwissProt: P0DJI8 Human
  • Unigene: 1955 Human
  • Unigene: 632144 Human
• 别名
  • Amyloid fibril protein AA antibody
  • Amyloid fibrils antibody
  • Amyloid protein A antibody

  • Fibrils antibody
  • MGC111216 antibody
  • OC antibody
  • PIG 4 antibody
  • PIG4 antibody
  • SAA 1 antibody
  • SAA 2 antibody
  • SAA antibody
  • SAA_HUMAN antibody
  • SAA1 antibody
  • SAA2 antibody
  • Serum amyloid A protein precursor antibody
  • Serum amyloid A1 isoform 1 antibody
  • Serum amyloid A1 isoform 2 antibody
  • Serum amyloid protein A(4-101) antibody
  • TP53I4 antibody
  • Tumor protein p53 inducible protein 4 antibody

  see all