The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
应用说明ELISA: Use at an assay dependent dilution.
WB: Use at a concentration of 0.1 - 0.5 µg/ml to allow visualization of 100ng/lane of recombinant human SAA. Predicted molecular weight: 14 kDa (unprocessed form).
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
功能Major acute phase reactant. Apolipoprotein of the HDL complex.
组织特异性Expressed by the liver; secreted in plasma.
疾病相关Note=Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function. Note=Elevated serum SSA protein levels may be associated with lung cancer.
序列相似性Belongs to the SAA family.
翻译后修饰This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end.