Anti-Serum Amyloid A抗体[38] (ab18707)

概述

  • 产品名称
    Anti-Serum Amyloid A抗体[38]
    参阅全部 Serum Amyloid A 一抗
  • 描述
    小鼠单克隆抗体[38] to Serum Amyloid A
  • 特异性
    ab18707 reacts with recombinant human SAA. It does not show any cross-reaction with other human cytokines or growth factors tested such as IL-1-beta, IL-8, MCAF, TGF-beta and EGF.
  • 经测试应用
    适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Highly purified human recombinant protein (MW: 12 kDa).

  • 常规说明

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

性能

应用

Our Abpromise guarantee covers the use of ab18707 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Predicted molecular weight: 12 kDa.

靶标

  • 功能
    Major acute phase reactant. Apolipoprotein of the HDL complex.
  • 组织特异性
    Expressed by the liver; secreted in plasma.
  • 疾病相关
    Note=Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.
    Note=Elevated serum SSA protein levels may be associated with lung cancer.
  • 序列相似性
    Belongs to the SAA family.
  • 翻译后修饰
    This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Amyloid fibril protein AA antibody
    • Amyloid fibrils antibody
    • Amyloid protein A antibody
    • Fibrils antibody
    • MGC111216 antibody
    • OC antibody
    • PIG 4 antibody
    • PIG4 antibody
    • SAA 1 antibody
    • SAA 2 antibody
    • SAA antibody
    • SAA_HUMAN antibody
    • SAA1 antibody
    • SAA2 antibody
    • Serum amyloid A protein precursor antibody
    • Serum amyloid A1 isoform 1 antibody
    • Serum amyloid A1 isoform 2 antibody
    • Serum amyloid protein A(4-101) antibody
    • TP53I4 antibody
    • Tumor protein p53 inducible protein 4 antibody
    see all

实验方案

文献

ab18707 has not yet been referenced specifically in any publications.

客户评价及客户问答

Thank you for your enquiry. The immunogen is a 12 KD recombinant SAA. The size fo SAA1, SAA2 and SAA4 are very similar and there is a possibility that the product can recognize all of them. Unfortunately, we have not confirmed this in the lab and w...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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