Anti-Serum Amyloid A抗体[291] (ab18713)

概述

  • 产品名称Anti-Serum Amyloid A抗体[291]
    参阅全部 Serum Amyloid A 一抗
  • 描述
    小鼠单克隆抗体[291] to Serum Amyloid A
  • 特异性Reacts with recombinant human SAA. Does not cross-react with other human cytokines or growth factors tested such as IL1ß, IL8, MCAF, TGFß and EGF.
  • 经测试应用适用于: IP, ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein (Human).

  • 阳性对照
    • 100ng/lane of recombinant protein

性能

应用

Our Abpromise guarantee covers the use of ab18713 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use at an assay dependent concentration.
ELISA Use at an assay dependent dilution.
WB Use a concentration of 0.1 - 0.5 µg/ml. Detects a band of approximately 12 kDa (predicted molecular weight: 14 kDa).

靶标

  • 功能Major acute phase reactant. Apolipoprotein of the HDL complex.
  • 组织特异性Expressed by the liver; secreted in plasma.
  • 疾病相关Note=Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.
    Note=Elevated serum SSA protein levels may be associated with lung cancer.
  • 序列相似性Belongs to the SAA family.
  • 翻译后修饰This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Amyloid fibril protein AA antibody
    • Amyloid fibrils antibody
    • Amyloid protein A antibody
    • Fibrils antibody
    • MGC111216 antibody
    • OC antibody
    • PIG 4 antibody
    • PIG4 antibody
    • SAA 1 antibody
    • SAA 2 antibody
    • SAA antibody
    • SAA_HUMAN antibody
    • SAA1 antibody
    • SAA2 antibody
    • Serum amyloid A protein precursor antibody
    • Serum amyloid A1 isoform 1 antibody
    • Serum amyloid A1 isoform 2 antibody
    • Serum amyloid protein A(4-101) antibody
    • TP53I4 antibody
    • Tumor protein p53 inducible protein 4 antibody
    see all

Anti-Serum Amyloid A antibody [291] (ab18713)参考文献

This product has been referenced in:
  • Wood SL  et al. Association of serum amyloid A protein and peptide fragments with prognosis in renal cancer. Br J Cancer 103:101-11 (2010). WB, IP ; Human . Read more (PubMed: 20531413) »
  • de Seny D  et al. Monomeric Calgranulins Measured by SELDI-TOF Mass Spectrometry and Calprotectin Measured by ELISA as Biomarkers in Arthritis. Clin Chem : (2008). Read more (PubMed: 18436720) »

See all 2 Publications for this product

Product Wall

Blocking

Inconclusive
Abreviews
Application Blocking
Sample Human Serum (monocytic cells)
Specification monocytic cells
Username

Abcam user community

Verified customer

提交于 Jun 13 2013

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunoprecipitation
Sample Human Tissue lysate - other (Human Serum)
Total protein in input 500 µg
Specification Human Serum
Immuno-precipitation step Other - Protein-G DynaL
Username

Abcam user community

Verified customer

提交于 Jun 28 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"