概述

  • 产品名称Anti-Sertad1抗体
    参阅全部 Sertad1 一抗
  • 描述
    兔多克隆抗体to Sertad1
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Saccharomyces cerevisiae, Drosophila melanogaster
  • 免疫原

    A region within a synthetic peptide: MLSKGLKRKR EEEEEKEPLA VDSWWLDPGH TAVAQAPPAV ASSSLFDLSV, corresponding to N terminal amino acids 1-50 of Human Sertad1

  • 阳性对照
    • WB: Jurkat cell lysate. IHC-P: human muscle tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab65446 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 5 µg/ml. Detects a band of approximately 25 kDa (predicted molecular weight: 25 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml.

靶标

  • 功能Acts at E2F-responsive promoters to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F-1/DP-1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of p16(INK4a).
  • 序列相似性Contains 1 SERTA domain.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CDK4 binding protein p34SEI antibody
    • CDK4 binding protein p34SEI1 antibody
    • CDK4-binding protein p34SEI1 antibody
    • SEI-1 antibody
    • SEI1 antibody
    • SERTA domain containing 1 antibody
    • SERTA domain-containing protein 1 antibody
    • SERTAD1 antibody
    • SRTD1_HUMAN antibody
    • Transcriptional regulator interacting with the PHD-bromodomain 1 antibody
    • TRIP Br1 antibody
    • TRIP-Br1 antibody
    see all

Anti-Sertad1 antibody 图像

  • Anti-Sertad1 antibody (ab65446) at 5 µg/ml + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 25 kDa
    Observed band size : 25 kDa
    Additional bands at : 70 kDa. We are unsure as to the identity of these extra bands.
  • ab65446, at 4µg/ml, staining Sertad1 in paraffin embedded human skeletal muscle cells (indicated by arrows) by Immunohistochemistry.

Anti-Sertad1 antibody (ab65446)参考文献

ab65446 has not yet been referenced specifically in any publications.

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