概述

  • 产品名称Anti-SERCA3 ATPase抗体
    参阅全部 SERCA3 ATPase 一抗
  • 描述
    兔多克隆抗体to SERCA3 ATPase
  • 特异性Detects sarcoplasmic or endoplasmic reticulum calcium ATPase 3 (SERC A3) human and rat recombinant protein. This antibody does not detect other SERCA isoforms.
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat, Dog, Human
  • 免疫原

    Synthetic peptide corresponding to Mouse SERCA3 ATPase aa 29-39.
    Sequence:

    VTDARERYGPN


    (Peptide available as ab4955)

性能

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应用

Our Abpromise guarantee covers the use of ab3339 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500. Detects a band of approximately 97 kDa (predicted molecular weight: 113 kDa).Can be blocked with SERCA3 ATPase peptide (ab4955). By Western blot, this antibody detects an ~97 kDa protein representing recombinant SERCA3 from rat samples.
IHC-P Use at an assay dependent concentration.

靶标

  • 功能This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.
  • 组织特异性Found in most tissues. Most abundant in thymus, trachea, salivary gland, spleen, bone marrow, lymph node, peripheral leukocytes, pancreas and colon. Also detected in fetal tissues.
  • 序列相似性Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
  • 细胞定位Nucleus membrane. Endoplasmic reticulum membrane. Sarcoplasmic reticulum membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Adenosine triphosphatase calcium antibody
    • AT2A3_HUMAN antibody
    • Atp2a3 antibody
    • ATPase Ca(2+) transporting ubiquitous antibody
    • ATPase Ca++ transporting ubiquitous antibody
    • Calcium pump 3 antibody
    • Calcium translocating P type ATPase antibody
    • Sarco/endoplasmic reticulum Ca2+ ATPase antibody
    • Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 antibody
    • SERCA 3 antibody
    • SERCA3 antibody
    • SERCA3b antibody
    • SR Ca(2+) ATPase 3 antibody
    • SR Ca(2+)-ATPase 3 antibody
    see all

Anti-SERCA3 ATPase antibody 图像



  • Predicted band size : 113 kDa


    Western blot of recombinant human SERCA3 ATPase expressed in E. coli using ab3339.

Anti-SERCA3 ATPase antibody (ab3339)参考文献

This product has been referenced in:
  • Poch E  et al. Functional characterization of alternatively spliced human SERCA3 transcripts. Am J Physiol 275:C1449-58 (1998). Read more (PubMed: 9843705) »

See 1 Publication for this product

Product Wall

Application Western blot
Sample Human Cell lysate - whole cell (HEK 293)
Loading amount 30 µg
Specification HEK 293
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 2% · Temperature: 25°C
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提交于 Aug 15 2007

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"