概述

  • 产品名称
  • 描述
    兔多克隆抗体to SERBP1
  • 经测试应用
    适用于: ICC, WB, ELISA, ICC/IF, IHC (PFA fixed)more details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to C-terminal residues of human SERBP1.

性能

应用

Our Abpromise guarantee covers the use of ab55993 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC Use at an assay dependent concentration.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 45 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.
IHC (PFA fixed) Use at an assay dependent concentration.

靶标

  • 功能
    May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.
  • 组织特异性
    Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain.
  • 细胞定位
    Cytoplasm. Nucleus. Cytoplasm > perinuclear region. Also found in perinuclear regions.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CGI 55 antibody
    • CHD3IP antibody
    • Chromodomain helicase DNA binding protein 3 interacting protein antibody
    • DKFZp564M2423 antibody
    • FLJ90489 antibody
    • HABP4L antibody
    • PAI 1 mRNA binding protein antibody
    • PAI RBP1 antibody
    • PAI-RBP1 antibody
    • PAI1 RNA-binding protein 1 antibody
    • PAIRB_HUMAN antibody
    • PAIRBP1 antibody
    • Plasminogen activator inhibitor 1 RNA binding protein antibody
    • Plasminogen activator inhibitor 1 RNA-binding protein antibody
    • Serbp1 antibody
    • SERPINE1 mRNA binding protein 1 antibody
    • SERPINE1 mRNA-binding protein 1 antibody
    see all

文献

This product has been referenced in:
  • Bashour NM & Wray S Progesterone directly and rapidly inhibits GnRH neuronal activity via progesterone receptor membrane component 1. Endocrinology 153:4457-69 (2012). Read more (PubMed: 22822163) »

See 1 Publication for this product

客户评价及客户问答

Abcam guarantees this product to work in the species/application used in this Abreview.
Application
Immunocytochemistry/ Immunofluorescence
Sample
Mouse Cell (fixed brain slices)
Specification
fixed brain slices
Fixative
Formaldehyde
Permeabilization
Yes - 0.3% Triton-X during blocking step
Blocking step
Normal Goat Serum as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: 25°C
Username

Mr. Nicholas Bashour

Verified customer

提交于 Apr 01 2011

Abcam guarantees this product to work in the species/application used in this Abreview.
Application
Immunohistochemistry (PFA fixed)
Sample
Mouse Tissue sections (uterus)
Specification
uterus
Username

Mr. Nicholas Bashour

Verified customer

提交于 Feb 17 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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