山羊多克隆抗体to Septin 3
This antibody is expected to recognise all three human isoforms of this protein.
Synthetic peptide: SELVPEPRPKPA, corresponding to N terminal amino acids 2-13 of Human Septin 3.
Principal Names – SEPT3; septin 3; SEP3; bK250D10.3; neuronal-specific septin 3.
Official Gene Symbol - SEPT3.
GenBank Accession Number – NP_061979; NP_663786; NP_663787.
LocusLink ID - 55964; 24050 (mouse); 56003 (rat).
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, 0.5mg/ml Tris, pH 7.3
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Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 40 kDa.Can be blocked with
Human Septin 3 peptide (ab22917).
Use at an assay dependent concentration. PubMed: 17564677
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis.
Belongs to the septin family.
Phosphorylated by PKG on serine residues. Phosphorylated by PKG on Ser-91.
Cytoplasm. Cytoplasm > cytoskeleton. Cell junction > synapse.
Information by UniProt
Neuronal specific septin 3 antibody
Anti-Septin 3 antibody (ab2518)参考文献
This product has been referenced in:
et al. Targeted disruption of Sept3, a heteromeric assembly partner of Sept5 and Sept7 in axons, has no effect on developing CNS neurons. J Neurochem 102:77-92 (2007).
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