产品名称 Anti-Septin 3抗体 参阅全部 Septin 3 一抗
山羊多克隆抗体to Septin 3
特异性 This antibody is expected to recognise all three human isoforms of this protein.
WB, IP more details
Synthetic peptide: SELVPEPRPKPA, corresponding to N terminal amino acids 2-13 of Human Septin 3.
常规说明 Principal Names – SEPT3; septin 3; SEP3; bK250D10.3; neuronal-specific septin 3.
Official Gene Symbol - SEPT3.
GenBank Accession Number – NP_061979; NP_663786; NP_663787.
LocusLink ID - 55964; 24050 (mouse); 56003 (rat).
存放说明 Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
存储溶液 Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, 0.5mg/ml Tris, pH 7.3
Concentration information loading...
纯度 IgG fraction
纯化说明 Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Immunizing Peptide (Blocking)
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 40 kDa.Can be blocked with
Human Septin 3 peptide (ab22917).
Use at an assay dependent concentration. PubMed: 17564677
功能 Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis.
序列相似性 Belongs to the septin family.
翻译后修饰 Phosphorylated by PKG on serine residues. Phosphorylated by PKG on Ser-91.
细胞定位 Cytoplasm. Cytoplasm > cytoskeleton. Cell junction > synapse.
Information by UniProt
Neuronal specific septin 3 antibody
Anti-Septin 3 antibody (ab2518)参考文献
This product has been referenced in:
et al. Targeted disruption of Sept3, a heteromeric assembly partner of Sept5 and Sept7 in axons, has no effect on developing CNS neurons. J Neurochem 102:77-92 (2007).
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