Anti-Septin 11抗体[998C6a] (ab84858)

概述

  • 产品名称
    Anti-Septin 11抗体[998C6a]
    参阅全部 Septin 11 一抗
  • 描述
    小鼠单克隆抗体[998C6a] to Septin 11
  • 经测试应用
    适用于: WB, Dot blotmore details
  • 种属反应性
    与反应: Recombinant fragment
    预测可用于: Human
  • 免疫原

    Recombinant fragment corresponsing to a region close to the N-terminus of Human Septin 11

性能

应用

Our Abpromise guarantee covers the use of ab84858 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 49 kDa.
Dot blot Use at an assay dependent dilution.

靶标

  • 功能
    Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity). During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy.
  • 组织特异性
    Widely expressed, except in leukocytes.
  • 疾病相关
    Note=A chromosomal aberration involving SEPT11 may be a cause of chronic neutrophilic leukemia. Translocation t(4;11)(q21;q23) with MLL/HRX.
  • 序列相似性
    Belongs to the septin family.
  • 细胞定位
    Cytoplasm > cytoskeleton. Cell junction > synapse. Cell projection > dendritic spine. Cell projection > axon. Partly colocalizes with stress fibers and microtubules. During bacterial infection, displays a collar shape structure next to actin at the pole of invading bacteria.
  • Information by UniProt
  • 数据库链接
  • 别名
    • SEP11_HUMAN antibody
    • SEPT 11 antibody
    • Sept11 antibody
    • Septin-11 antibody
    • Septin11 antibody
    see all

图片

  • Anti-Septin 11 antibody [998C6a] (ab84858) + immunogen (recombinant fragment of Human protein)

    Predicted band size : 49 kDa

实验方案

文献

ab84858 has not yet been referenced specifically in any publications.

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