概述

  • 产品名称Anti-SEPT4抗体
    参阅全部 SEPT4 一抗
  • 描述
    兔多克隆抗体to SEPT4
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide corresponding to Human SEPT4 aa 247-266 conjugated to Keyhole Limpet Haemocyanin (KLH).
    Sequence:

    KNIQDNRVHCCLYFISPFGHG

  • 阳性对照
    • Whole cell extract of HEK 293 cells transfected with ARTS expression plasmid.

性能

应用

Our Abpromise guarantee covers the use of ab10441 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/15000. Detects a band of approximately 32 kDa.

靶标

  • 功能Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion. Isoform ARTS, but not the other isoforms, is required for the induction of cell death mediated by TGF-beta and by other apoptotic stimuli.
  • 组织特异性Widely expressed in adult and fetal tissues with highest expression in adult brain (at protein level), heart, liver and adrenal gland and fetal heart, kidney, liver and lung. Also expressed in colorectal cancers and malignant melanomas. Expressed in platelets.
  • 序列相似性Belongs to the septin family.
  • 细胞定位Cytoplasm. Cytoplasm > cytoskeleton. In platelets, found in areas surrounding alpha-granules and Mitochondrion. Nucleus. While predominantly localized in the mitochondria under resting conditions, isoform ARTS translocates into the nucleus after TGF-beta treatment and apoptosis induction.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Apoptosis-related protein in the TGF-beta signaling pathway antibody
    • ARTS antibody
    • Bradeion antibody
    • Bradeion beta antibody
    • Brain protein H5 antibody
    • CE5B3 antibody
    • CE5B3 beta antibody
    • Cell division control-related protein 2 antibody
    • Cerebral protein 7 antibody
    • H5 antibody
    • hCDCREL-2 antibody
    • hucep-7 antibody
    • MART antibody
    • Peanut-like protein 2 antibody
    • PNUTL2 antibody
    • SEP 4 antibody
    • SEP4 antibody
    • Sept4 antibody
    • SEPT4_HUMAN antibody
    • Septin M antibody
    • Septin-4 antibody
    see all

Anti-SEPT4 antibody (ab10441)参考文献

ab10441 has not yet been referenced specifically in any publications.

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