概述

性能

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应用

Our Abpromise guarantee covers the use of ab3657 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
IHC-P
  • 应用说明ELISA: 1/1000.
    IHC-P: 1/50 - 1/100.
    WB: 1/100 - 1/500.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    Expected molecular weight: 73.351 kDa (from SwissProt Q9P0U3).
  • 靶标

    • 功能Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1, which decreases its transcriptional repression activity.
    • 组织特异性Highly expressed in testis. Expressed at lower levels in thymus, pancreas, spleen, liver, ovary and small intestine.
    • 序列相似性Belongs to the peptidase C48 family.
    • 细胞定位Nucleus. Cytoplasm. Shuttles between cytoplasm and nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • SENP 1 antibody
      • SENP1 antibody
      • SENP1_HUMAN antibody
      • Sentrin specific protease 1 antibody
      • Sentrin-specific protease 1 antibody
      • Sentrin/SUMO specific protease 1 antibody
      • Sentrin/SUMO specific protease antibody
      • Sentrin/SUMO specific protease SENP 1 antibody
      • Sentrin/SUMO specific protease SENP1 antibody
      • Sentrin/SUMO-specific protease SENP1 antibody
      • SUMO1/sentrin specific peptidase 1 antibody
      • SUMO1/sentrin specific protease 1 antibody
      • SuPr 2 antibody
      • SuPr2 antibody
      see all

    Anti-SENP1 antibody 图像

    • Western blot analysis of SENP 1 in whole HL60 cell lysate using ab3657 (Lane B) but not pre-immune serum (lane A). Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
    • ab3657 staining SENP1 in human breast carcinoma (BC) tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).

    Anti-SENP1 antibody (ab3657)参考文献

    ab3657 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"