, corresponding to amino acids 43-59 of Human SENP 1.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
PBS with 0.1% sodium azide
Concentration information loading...
Protein G purified
This antibody is purified through a protein G column and eluted out with both high and low pH buffers.
It is neutralized immediately after elution, followed by dialysis against PBS.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-P: 1/50 - 1/100.
WB: 1/100 - 1/500.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Expected molecular weight: 73.351 kDa (from SwissProt Q9P0U3).
Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1, which decreases its transcriptional repression activity.
Highly expressed in testis. Expressed at lower levels in thymus, pancreas, spleen, liver, ovary and small intestine.
Belongs to the peptidase C48 family.
Nucleus. Cytoplasm. Shuttles between cytoplasm and nucleus.
Information by UniProt
SENP 1 antibody
Western blot - SENP1 antibody (ab3657)
Western blot analysis of SENP 1 in whole HL60 cell lysate using ab3657 (Lane B) but not pre-immune serum (lane A). Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - SENP1 antibody (ab3657)
ab3657 staining SENP1 in human breast carcinoma (BC) tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"