概述

  • 产品名称Anti-SENP1抗体
    参阅全部 SENP1 一抗
  • 描述
    兔多克隆抗体to SENP1
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide:

    CKRKEFDTNGWQLFSKK

    , corresponding to amino acids 575-590 of Human SENP 1.

  • 阳性对照
    • HL60 whole cell lysate.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab3656 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明Western blotting: 1/100 - 1/500.
    ELISA: 1/1000.
    Not tested in other applications.

    Optimal dilutions / concentrations should be determined by the end user.

    Expected molecular weight: 73.351 kDa (from SwissProt Q9P0U3).
  • 靶标

    • 功能Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1, which decreases its transcriptional repression activity.
    • 组织特异性Highly expressed in testis. Expressed at lower levels in thymus, pancreas, spleen, liver, ovary and small intestine.
    • 序列相似性Belongs to the peptidase C48 family.
    • 细胞定位Nucleus. Cytoplasm. Shuttles between cytoplasm and nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • SENP 1 antibody
      • SENP1 antibody
      • SENP1_HUMAN antibody
      • Sentrin specific protease 1 antibody
      • Sentrin-specific protease 1 antibody
      • Sentrin/SUMO specific protease 1 antibody
      • Sentrin/SUMO specific protease antibody
      • Sentrin/SUMO specific protease SENP 1 antibody
      • Sentrin/SUMO specific protease SENP1 antibody
      • Sentrin/SUMO-specific protease SENP1 antibody
      • SUMO1/sentrin specific peptidase 1 antibody
      • SUMO1/sentrin specific protease 1 antibody
      • SuPr 2 antibody
      • SuPr2 antibody
      see all

    Anti-SENP1 antibody 图像

    • Western blot analysis SENP 1 in whole HL60 cell lysate. SENP1 (Arrow) was detected using ab3656 (Lane B) but not pre-immune serum (lane A). Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

    Anti-SENP1 antibody (ab3656)参考文献

    This product has been referenced in:
    • Ni RS  et al. Detection of differentially expressed genes and association with clinicopathological features in laryngeal squamous cell carcinoma. Oncol Lett 4:1354-1360 (2012). WB ; Human . Read more (PubMed: 23226807) »
    • Dai XQ  et al. SUMOylation regulates insulin exocytosis downstream of secretory granule docking in rodents and humans. Diabetes 60:838-47 (2011). WB ; Human, Mouse . Read more (PubMed: 21266332) »

    See all 2 Publications for this product

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