Anti-Semaphorin 7a抗体[MM0537-99D22] (ab90242)


  • 产品名称Anti-Semaphorin 7a抗体[MM0537-99D22]
    参阅全部 Semaphorin 7a 一抗
  • 描述
    大鼠单克隆抗体[MM0537-99D22] to Semaphorin 7a
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: , corresponding to amino acids 46-645 of Human Semaphorin 7a



Our Abpromise guarantee covers the use of ab90242 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
  • 应用说明WB: 1/500 - 1/1000. Predicted molecular weight: 75 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
    • 组织特异性Detected in skin keratinocytes and on endothelial cells from skin blood vessels (at protein level). Expressed in fibroblasts, keratinocytes, melanocytes, placenta, testis, ovary, spleen, brain, spinal chord, lung, heart, adrenal gland, lymph nodes, thymus, intestine and kidney.
    • 序列相似性Belongs to the semaphorin family.
      Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
      Contains 1 PSI domain.
      Contains 1 Sema domain.
    • 细胞定位Cell membrane. Detected in a punctate pattern on the cell membrane of basal and supra-basal skin keratinocytes.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CD 108 antibody
      • CD108 antibody
      • CD108 antigen antibody
      • CDw108 antibody
      • H Sema K1 antibody
      • H Sema L antibody
      • H-SEMA-K1 antibody
      • H-Sema-L antibody
      • JMH antibody
      • JMH blood group antigen antibody
      • John Milton Hagen blood group H Sema K1 antibody
      • John Milton Hargen human blood group Ag antibody
      • John-Milton-Hargen human blood group Ag antibody
      • MGC126692 antibody
      • MGC126696 antibody
      • SEM7A_HUMAN antibody
      • Sema domain immunoglobulin domain (Ig) and GPI membrane anchor 7A antibody
      • Sema K1 antibody
      • Sema L antibody
      • SEMA7A antibody
      • SEMAK1 antibody
      • SEMAL antibody
      • Semaphorin 7A GPI membrane anchor antibody
      • Semaphorin K1 antibody
      • Semaphorin L antibody
      • Semaphorin-7A antibody
      • Semaphorin-K1 antibody
      • Semaphorin-L antibody
      • Semaphorin7a antibody
      see all

    Anti-Semaphorin 7a antibody [MM0537-99D22] 图像

    • Anti-Semaphorin 7a antibody [MM0537-99D22] (ab90242) at 1/500 dilution + Human brain tissue

      Predicted band size : 75 kDa

    Anti-Semaphorin 7a antibody [MM0537-99D22] (ab90242)参考文献

    ab90242 has not yet been referenced specifically in any publications.

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    I have had the opportunity to speak with the lab. The Western blot was tested using the immunogen (extracellular domain of the human protein), with antibody concentration around 1microgram/ml,. Unfortunately do n...

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